Medication Compliance in Type 2 Diabetes Patients: HbA1c and Lipid Profile at Aulia Jombang Clinic 2020
Article Sidebar
Main Article Content
Page: 1888-1896
Abstract
Diabetes Mellitus (DM) is a chronic metabolic disease characterized by high blood sugar levels due to insulin secretion or work defects. Poor treatment adherence leads to uncontrolled glycemic levels and complications. Therefore, ensuring patient adherence to therapy and reducing HbA1c and lipid profiles is essential. This research employs an observational, cross-sectional design, using non-probability purposive sampling to select 55 respondents via the Slovin formula. The study examines medication adherence as the independent variable, Hba1c levels, and lipid profile as the dependent variables. Data analysis involves SPSS, utilizing univariate and bivariate methods for ordinal and nominal scales. MMAS-8 questionnaire assesses the knowledge, while data comes from questionnaires and medical records of type 2 DM patients at Aulia Jombang Clinic. Study findings showed notable adherence to treatment, with 38 respondents (60.9%) complying and 17 (30.1%) not. Chi-square tests yielded significance, p values: HbA1c 0.012, LDL 0.035, total cholesterol 0.008, triacylglycerides 0.011, and HDL 0.002, based on MMAS-8 questionnaire data. In conclusion, the results indicate statistical significance (p-value < 0,05), so there is a positive correlation coefficient, indicating that higher levels of treatment adherence are associated with more optimal HbA1c control and lipid profiles.
Downloads
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
References
Adikusuma, W., & Qiyaam, N. (2017). Hubungan Tingkat Kepatuhan Minum Obat Antidiabetik Oral Terhadap Kadar Hemoglobin Terglikasi (Hba1c) Pada Pasien Diabetes Melitus Tipe 2. Jurnal Ilmiah Ibnu Sina (JIIS): Ilmu Farmasi Dan Kesehatan, 2(2), 279–286. https://doi.org/10.36387/jiis.v2i2.105
Adinda Putri, Z. (2021). Literature Reviex: Hubungan HbA1c Dengan Kadar Profil Lipid Pada Penderita Diabetes Melitus Tipe 2 (Skripsi). Sekolah Tinggi Ilmu Kesehatan Insan Cendekia Medika Jombang.
Artha, I. M. J. R., Bhargah, A., Dharmawan, N. K., Pande, U. W., Triyana, K. A., Maharishi, P. A., . . . Rina, I. K. (2019).
High level of individual lipid profile and lipid ratio as a predictive marker of poor glycemic control in type-2 diabetes mellitus
Vascular Health and Risk Management, Volume 15, 149–157. https://doi.org/10.2147/vhrm.s209830Driyah, S., Bs, L., & Dk, K. T. (2019). Korelasi Kontrol Glikemik dengan HDL dan Small-Dense LDL pada Penderita Diabetes Melitus dengan Komplikasi Jantung Koroner di RSUP Dr. Kariadi Semarang, Jawa Tengah. Journal Biotek Medisiana Indonesia : The Indonesian Journal of Biotechnology Medicine (E-journal), 8(1), 67–75. https://doi.org/10.22435/jbmi.v8i1.2585
Fahrial Syam, A., Alwi, I., & Setiati, S. (2015). Buku Ajar Ilmu Penyakit Dalam (6th ed., Vol. 6). Jakarta, Jawa Barat, Indonesia: Interna Publishing.
Hari Diabetes Sedunia Tahun 2018 - Direktorat P2PTM. (n.d.). Retrieved from https://p2ptm.kemkes.go.id/tag/hari-diabetes-sedunia-tahun-2018
Iloh, G. U. P., Ofoedu, J. N., Uchenna, N. P., Nkwa, A. A., & Uchamma, G. E. (2012). Blood glucose control and medication adherence among adult type 2 diabetic Nigerians attending a primary care clinic in an under-resourced environment of eastern Nigeria. North American Journal of Medical Sciences, 4(7), 310. https://doi.org/10.4103/1947-2714.98590
Kasper, D. L., Fauci, A. S., Hauser, S. L., Longo, D. L., Jameson, J. L., & Loscalzo, J. (2015). Harrison’s Principles of Internal Medicine 19/E (Vol.1 & 2) (ebook). McGraw Hill Professional.
Moon, S. J., Lee, W. Y., Hwang, J., Hong, Y. P., & Morisky, D. E. (2017). Accuracy of a screening tool for medication adherence: A systematic review and meta-analysis of the Morisky Medication Adherence Scale-8. PLOS ONE, 12(11), e0187139. https://doi.org/10.1371/journal.pone.0187139
Perkumpulan Endokrinologi Indonesia [Perkeni]. (2019). Pedoman Pengelolaan Dislipidemi di Indonesia 2019. PB Perkeni.
Prasetyorini, T., Cindy, & Salbiah. (2021). Correlation of HbA1c levels with Triglyceride, LDL and HDL levels in Type 2 Diabetes Mellitus Patients. International Journal of Science and Society, 3(2), 138–145. https://doi.org/10.54783/ijsoc.v3i2.325
Puspitasari, P., & Aliviameita, A. (2018). Hubungan profil lipid dengan kadar glukosa darah pada pasien diabetes mellitus. Medicra (Journal of Medical Laboratory Science/Technology), 1(2), 77–83. https://doi.org/10.21070/medicra.v1i2.1831
Ramadhan, N. G., & Marissa, N. (2015). Karakteristik Penderita Diabetes Mellitus Tipe 2 Berdasarkan Kadar Hba1c Di Puskesmas Jayabaru Kota Banda Aceh. Sel, 2(2). https://doi.org/10.22435/sel.v2i2.4637.49-56
Rdeliani, I. G. a. I., Ratnasari, P. M. D., & Yuliawati, A. N. (2021). Analisis Hubungan Kepatuhan Pengobatan Terhadap Kontrol Glikemik Pasien Diabetes Melitus Tipe 2di Instalasi Rawat Jalan Rumah Sakit “X” Buleleng. JIIS (Jurnal Ilmiah Ibnu Sina): Ilmu Farmasi Dan Kesehatan, 6(2), 331–340. https://doi.org/10.36387/jiis.v6i2.739
Rokom. (2012, May 30). BPJS KESEHATAN: Sistem Jaminan Kesehatan di Indonesia. Retrieved from https://sehatnegeriku.kemkes.go.id/baca/rilis-media/20120530/114176/bpjs-kesehatan-sistem-jaminan-kesehatan-di-indonesia/
Sendekie, A. K., Netere, A. K., Kasahun, A. E., & Belachew, E. A. (2022). Medication adherence and its impact on glycemic control in type 2 diabetes mellitus patients with comorbidity: A multicenter cross-sectional study in Northwest Ethiopia. PLOS ONE, 17(9), e0274971. https://doi.org/10.1371/journal.pone.0274971
Sumampouw, H. C., & Halim, S. (2019). Korelasi status glikemik dengan profil lipid pada penderita Diabetes Melitus tipe 2 di Rumah Sakit Sumber Waras dan Rumah Sakit Hermina Kemayoran tahun 2015-2017. Tarumanagara Medical Journal, 1(2), 319–328. https://doi.org/10.24912/tmj.v1i2.3852
Suyatno, S., Kurniawan, B., & Suharmanto, S. (2021). Hubungan Profil Lipid Terhadap Kontrol Glikemik DM Tipe 2 Peserta Program Pengelolaan Penyakit Kronis (Prolanis) di fasilitas Kesehatan Provinsi Lampung Tahun 2021. Jurnal Analis Kesehatan, 10(1), 35. https://doi.org/10.26630/jak.v10i1.2719
Usnaini, L., Musyarrafah, M., Wanadiatri, H., & Winangun, I. G. P. (2020). Hubungan Kepatuhan Konsumsi Obat Antidiabetik Terhadap Kadar Hba1c Pada Pasien Dm Tipe 2 Di Rumah Sakit Umum Daerah Provinsi Nusa Tenggara Barat Tahun 2019. Jurnal Kedokteran, 5(2), 69. https://doi.org/10.36679/kedokteran.v5i2.224
Wahab, Z. (2015). Profil Lipid sebagai Kontrol Glikemik pada Pasien Diabetes Mellitus Tipe II. Retrieved from https://jurnal.unimus.ac.id/index.php/kedokteran/article/view/2569/2419
Wang, L., Wang, Q., Hong, Y. H., Ojo, O., Jiang, Q., Hou, Y., . . . Wang, X. (2018). The Effect of Low-Carbohydrate Diet on Glycemic Control in Patients with Type 2 Diabetes Mellitus. Nutrients, 10(6), 661. https://doi.org/10.3390/nu10060661
Wang, S., Ji, X., Zhang, Z., & Xue, F. (2020). Relationship between Lipid Profiles and Glycemic Control Among Patients with Type 2 Diabetes in Qingdao, China. International Journal of Environmental Research and Public Health, 17(15), 5317. https://doi.org/10.3390/ijerph17155317
Zulfian, Z. Z., Artini, I. G. A., & Barowalah, R. A. (2020). Korelasi antara Nilai HbA1c dengan Kadar Trigliserida Pasien Diabetes Mellitus Tipe 2. Sandi Husada : Jurnal Ilmiah Kesehatan, 11(1), 237–242. https://doi.org/10.35816/jiskh.v11i1.257