Journal of Pharmaceutical and Sciences https://journal-jps.com/new/index.php/jps <p>Thank you for visiting the Journal of Pharmaceutical and Sciences (e-ISSN: 2656-3088). It is with great pleasure that the first issue of the JJournal of Pharmaceutical and Sciences is released to the academic world, which is intended to accommodate the needs of researchers to publish their work. The Faculty of Pharmacy at Tjut Nyak Dhien University publishes this journal. This journal's publisher is dedicated to advancing research and knowledge in the pharmaceutical, science, and health fields. Articles that have been published can be accessed and downloaded online by the public (open-access journal). Manuscripts can be submitted to the Journal of Pharmaceutical and Sciences in Indonesian and English. The Journal of Pharmaceutical and Life Sciences has been accredited by the Directorate General of Higher Education, Ministry of Research, Technology, and Higher Education, Republic of Indonesia. With a SINTA accreditation rating of 4. Certificate No. 164/E/KPT/2021 (<a href="https://drive.google.com/file/d/1Uc_FFB7Pi9qAophB2f5Ggghw7BNCA-wu/view">download Certificate</a>).</p> <p><strong>Journal Migration</strong></p> <p>As of January 1, 2023, Volume 6 number 1, the Journal of Pharmaceutical and Sciences has migrated to a new website at <a href="https://journal-jps.com/new">https://journal-jps.com/new</a>. While the old version (volume 1 to volume 5) can still be accessed as usual at the URL: <a href="https://lama.journal-jps.com">https://lama.journal-jps.com</a> or <a href="https://journal-jps.com/index.php/jps/issue/archive">https://journal-jps.com/index.php/jps/issue/archive</a>.</p> <p><a href="https://journal-jps.com/new/index.php/jps/about/submissions"><strong>Submit your manuscript via the new website</strong></a></p> en-US admin@journal-jps.com (Salman) journal.jps1@gmail.com (Popi Melsindy) Mon, 07 Jul 2025 11:29:37 -0700 OJS 3.3.0.13 http://blogs.law.harvard.edu/tech/rss 60 Comparison of Phenolic and Antioxidant Contents in Tea Brewing and Kombucha Tea Variants by Visible Spectrophotometry https://journal-jps.com/new/index.php/jps/article/view/952 <p>One of the most widely consumed aromatic beverages in the world is tea. Tea shoots are rich in polyphenolic compounds that function as antioxidants. Not many people know that tea can be fermented with a type of bacteria and yeast culture that can be consumed as a drink for health known as kombucha tea. The health benefits of consuming kombucha tea as anti-carcinogenic, anti-diabetic, detoxification, increased immune response, treating stomach ulcers and lowering cholesterol levels as well as high blood pressure. The purpose of this study was to determine the total phenolic content and antioxidant activity as well as the comparison of total phenolic content and antioxidant activity in tea brewing variations with kombucha tea variations. The methods carried out include testing the total phenolic content and antioxidant activity using the DPPH method on tea brewing variants and kombucha tea variants by visible spectrophotometry.mThe results of total phenolic content in black tea, green tea, and oolong tea were 24,480 mgGAE/g, 26,538 mgGAE/g, and 38,427 mgGAE/g, respectively, while kombucha black tea, green tea, and oolong tea were 39,264 mgGAE/g, 58,581 mgGAE/g, and 64,299 mgGAE/g, respectively. Brewed black tea, green tea, and oolong tea have antioxidant activity with IC50 values of 105,68 ppm in teh moderate category, 81,59 ppm in teh strong category, and 56,25 ppm in the strong category, respectively. In kombucha black tea, green tea, and oolong tea have antioxidant activity with IC50 values respectively 101,60 ppm with moderate category, 55,82 ppm with strong category, and 39,69 ppm with very strong category. While teh vitamin C comparator has antioxidant activity with an IC50 value of 3,22 ppm with a very strong category.</p> Dini Maghfirah , Ainil Fithri Pulungan , Ridwanto, Rafita Yuniarti Copyright (c) 2025 Dini Maghfirah , Ainil Fithri Pulungan , Ridwanto, Rafita Yuniarti https://creativecommons.org/licenses/by-nc-sa/4.0 https://journal-jps.com/new/index.php/jps/article/view/952 Mon, 07 Jul 2025 00:00:00 -0700 Activity Test of Ethanol Extract of Bandotan Leaves (Ageratum conyzoides L.) on Healing of Burn Wounds in Rats (Rattus norvegicus) with Diabetes Mellitus https://journal-jps.com/new/index.php/jps/article/view/935 <p>Burn wounds in patients with diabetes mellitus experience impaired healing due to chronic hyperglycemia. This study aims to identify phytochemical compounds, analyze the characteristics of crude drugs, and test the activity of ethanol extracts of bandotan leaves (<em>Ageratum conyzoides</em> L.) on burn wound healing in rats (<em>Rattus norvegicus</em>) with diabetes mellitus, including histological evaluation of wound tissue. Screening results showed that the extract contains active compounds such as alkaloids, flavonoids, tannins, saponins, quinones, and steroids. Herbal material characterization met standards for moisture and ash content but did not meet standards for water-soluble and ethanol-soluble extract content. The extract gel formulation was tested at three concentrations (5%, 10%, 15%). Efficacy tests showed that the 15% gel accelerated wound healing by 100% by day 15, with histological findings indicating increased numbers of fibroblasts, collagen fibers, and capillary blood vessels. This study concludes that ethanol extract of bandotan leaves has potential as an effective wound healing agent, particularly in diabetic conditions.</p> Nur Afika, Muhammad Yunus , Erida Novriani Copyright (c) 2025 Nur Afika, Muhammad Yunus , Erida Novriani https://creativecommons.org/licenses/by-nc-sa/4.0 https://journal-jps.com/new/index.php/jps/article/view/935 Fri, 11 Jul 2025 00:00:00 -0700