Test of the effectiveness of white goroho banana weevil extract gel preparation (Musa acuminafe, sp) against the healing of white rat burns (Rattus nornvegicus)

Article Sidebar

pdf (Bahasa Indonesia)
Published: Jul 13, 2023
DOI: https://doi.org/10.36490/journal-jps.com.v6i3.184
Keywords:
Effectiveness, Burns, gel formulations

Main Article Content

Martina G. Laloan
Program Studi Farmasi,Fakultas MIPA,Universitas Kristen Indonesia Tomohon
Douglas N. Pareta
Program Studi Farmasi,Fakultas MIPA,Universitas Kristen Indonesia Tomohon
Selvana S. Tulandi
Program Studi Farmasi,Fakultas MIPA,Universitas Kristen Indonesia Tomohon
Yessie K. Lengkey
Program Studi Biologi, Fakultas MIPA,Universitas Kristen Indonesia Tomohon
Christel N. Sambou
Program Studi Farmasi,Fakultas MIPA,Universitas Kristen Indonesia Tomohon

Page: 1026-1033

Abstract

Natural wealth has a variety of herbal plants, plants that are included in it efficacious as medicine. Traditional medicine, is an ingredient or herb that is usually used as traditional medicine and is used to accelerate the healing of diseases, one of the plants used to accelerate wound healing is the white goroho banana weevil (Musa acuminafe, sp). This study aimed to determine the effectiveness of banana weevil gel preparations against healing burns in white rats (Rattus norvegicus). The test animals used were 15 rats. A burn of 2.5 cm was made on the back of the mouse using metal coins. The method used in this study is in the form of laboratory experiments. This study used a Complete Randomized Design (RAL) consisting of 5 treatments, including 1 negative control, 1 positive control (bioplacenton), and 3 stratified concentrations, namely 5% concentration gel, 10% concentration gel and 15% concentration gel with 3 repetitions each. The treatment is carried out for 14 days. The results of measuring wound diameter in rats based on the results showed that banana weevil extract gel concentration of 15% provided a healing effect more effective than other extracts.

Downloads

Download data is not yet available.

Article Details

How to Cite
Laloan, M. G., Pareta, D. . N., Tulandi, S. S., Lengkey, Y. K., & Sambou, C. N. (2023). Test of the effectiveness of white goroho banana weevil extract gel preparation (Musa acuminafe, sp) against the healing of white rat burns (Rattus nornvegicus). Journal of Pharmaceutical and Sciences, 6(3), 1026–1033. https://doi.org/10.36490/journal-jps.com.v6i3.184
Issue
JPS Volume 6 Nomor 3(2023)
Section
Original Articles
Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Crossref
Scopus
Google Scholar
Europe PMC

References

Aini, N, M.D. Maghfoer, K. Yurlisa. 2019 Tanaman Lokal Indonesia NA (Malang: UB Press,).

Afianti, Hanum Pramuji dan Mimiek Murrukmihadi. 2015. Pengaruh Variasi kadar Gelling Agent HPMC Terhadap Sifat Fisik dan Aktivitas Antibakteri Sediaan Gel Ekstrak Etanolik Daun Kemangi (Ocimum basilicum L. forma citratum Back.). Fakultas Farmasi. Universitas Gadjah Mada. Yogyakarta.

Izzati, U.F. 2015. Efektivitas Penyembuhan Luka Bakar Salep Ekstrak Etanol Daun Senggani (Melastoma malabatharicum L.) Pada Tikus (Rattus norvegicus) Jantan Galur Wistar. Skripsi Farmasi. Pontianak: Universitas Tanjungpura.

Karamoy, V.M., Loho, A.E., Lolowang, T,F. 2017. Analisis Nilai Tambah Pisang Goroho (musa acuminafe, sp). Agri-Sosioekonomi. USRAT.

Negara, R.F.K., Ratnawati, R., dan Dina, D.S.L.I. Juni, 2014. Pengaruh Perawatan Luka Bakar Derajat II Menggunakan EKstrak Etanol Daun Sirih (Piper betle Linn.) Terhadap Peningkatan Ketebalan Jaringan Granulasi pada Tikus Putih (Rattus norvegicus) Jantan Galur Wistar). Majalah Kesehatan FKUB, hlm 86-94.

Prasongko, E.T, M Lailiyah, W Muzayyidin. (2020) Formulasi Dan Uji Efektivitas Gel Ekstrak Daun Kedondong (Spondias dulcis F.) Terhadap Luka Bakar Pada Tikus Wistar (Rattus novergicus). Jurnal Wiyata 007 (01): 27–36.

Hamzah B.U. 2013. Teori Motivasi dan Pengukurannya. Jakarta: Bumi Aksara

Hatjarul, A., S. 2018. Uji Efektivitas Sediaan Gel Ekstrak Etanol Daun Cabai Rawit (Capsicum frutescens L.) Terhadap Pertumbuhan Bakteri Penyebab Jerawat. Jurnal Farmasi Mahalayati, 2(2); 70-80.

Larasati, D.A, and E. Apriliana. 2016 Efek Potensial Daun Kemangi (Ocimum basilicum L.) Sebagai Pemanfaatan Hand Sanitizer The Potential Effect of Basil Leaves (Ocimum basilicum L.) as Utilization of Hand Sanitizer, Jurnal Majority 5 : 124–29.

Ngatimin, A, S. Nur. 2019. Teknik Menanggulangi Serangga Hama Kehutanan Menggunakan Metabolit Sekunder Tanaman. Jakarta.

Ramdani N.F,C. Mambo, dan Wuisan. 2014. Uji Efek Daun Kemangi (Ocimum basilium L) Terhadap Penyembuhan Luka Insisi pada Kelinci (Oryctolagus Cuniculus).

Rustam, E, and H Arifin. 2020. Efek Analgetik Ekstrak Etanol Daun Kemangi (Ocimum sanctum L.) Pada Mencit Putih Jantan. Jurnal Farmasi Higea. 12(1): 40–47.

Saputri, F.C, and Z. Rita. 2016. Uji Aktivitas Anti-Inflamasi Minyak Atsiri Daun Kemangi (Ocimum americanum L.) pada Tikus Putih Jantan yang Diinduksi Karagenan, Pharmaceutical Sciences and Research: Vol. 3: No. 3, Article 1 : 5-6.

Rahayuningsih, T. 2012. Penatalaksana Luka Bakar Combustio. Volume 08, Akper Poltekes Bhakti Mulia Sukoharjo.

Suyanti & Supriyadi, Ahmad. (2008). Pisang, Budidaya, Pengolahan & Prospek Pasar. Edisi Revisi. Penebar Swadaya. Jakarta.