Testing the Effectiveness of Ethanol Extract from Pandan Laeves (Pandanus amarylifolius Roxb) As a Healer of Incision Wounds in White Rats (Rattus norvegicus)
Article Sidebar
Main Article Content
Page: 974-979
Abstract
An incision is a wound that splits the skin area due to being cut by a sharp object. Indonesian people use medicinal plants very much in traditional or modern medicine. One of the plants that can be used as a medicinal ingredient is fragrant pandan leaves which can accelerate the wound healing process. This study aims to determine the level of effectiveness of pandan leaf extract as a healer for cuts. This study used 15 white rats which were then slashed on their backs using a 1 cm long scalpel with a depth of ± 2 mm. This study used a laboratory experiment using a completely randomized design consisting of 5 treatment groups, including 1 negative control, positive control (10 percent povidone iodine) and 3 graded concentrations, namely pandan leaf extract concentrations of 5.10 to 15 percent with 2 each. repetition times. The results of measuring the length of the wound in rats showed that fragrant pandan leaf extract with a concentration of 10 percent and 15 percent had the same effectiveness.
Downloads
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
References
Firawati dan Karlina. 2017. The Effect of Infusa Pandan Wangi (Pandanus amaryllifolius Roxb) to the Growth of Staphylococcus Aureus. Jurnal Majalah Farmasi, Universitas Indonesia Timur Makassar. 14(01): 20-21.
Hastono, S.P., dan L, Sabri. 2013. Statistik Kesehatan. Penerbit Rajagrafindo Persada. Jakarta.
Kevin. 2019. Carica Pepaya peel mediated synthesis of silver nanoparticles and its antibacterial activity against human pathogens. Journal of Applied Research and Technology. 15(3): 413-422.
Lostapa, I.W.F.W., A.A.G.J. Wardhita, I.G.A.G.P. Pamayun, L.M. Sudimartini. 2016. Kecepatan kesembuhan luka insisi yang diberi amoksisilin dan asam mefenamat pada tikus putih. Jurnal Universitas Udayana. 8(2). 172-179.
Marjoni, R. M. 2016. Dasar-Dasar Fitokimia untuk Diploma III Farmasi. Ed. 1. Penerbit Trans Info Media. Jakarta. hal. 143-147.
Oeleu, K. Y. 2022. Uji Aktivitas Gel Ekstrak Daun Pandan Wangi (Pandanus amaryllifolius Roxb) Terhadap Penyembuhan Luka Bakar Buatan Pada Kelinci New Zealand. Jurnal Ilmiah Kesehatan Ar-Rum Salatiga. 6(2): 52-53.
Rahman, R.T.A. 2015. Analisis Statistik Penelitian Kesehatan. Penerbit In Media. Bogor.
Rokhmah, N.N., Yulianita., dan R.A, Putra. 2021. Efektivitas Gel Daun Pandan Sebagai Luka Bakar Pada Tikus Putih. Jurnal Pharmacoscript, Fakultas Matematika Ilmu Pengetahuan Alam Universitas Pakuan Bogor. 4(2): 131-132.
Santoso, S. 2014. Panduan Lengkap SPSS. Penerbit Alexmedia Computindo. Jakarta.
Siregar, S. 2014. Statistika Deskriptif untuk Penelitian. Penerbit Rajagrafindo Grup. Jakarta.
Sjamsuhidajat, J. (2010). Buku Ajar Ilmu Bedah. Ed 3. ECG. Jakarta. hal 706-708.
Sunyoto, D dan A, Setiawan. 2013. Statistik Kesehatan. Penerbit Nuha Medika. Yogyakarta.
Tapehe, Y. 2015. Statistika dan Rancangan Percobaan. Penerbit Buku Kedokteran. Jakarta.
Wientarsih, L., W, Winarsih., N.L, dan Sutardi. 2012. Aktivitas Penyembuhan Luka Oleh Gel Fraksi Etil Asetat Rimpang Kunyit pada Mencit Hiperglikemik. Jurnal Veteriner, Fakultas Kedokteran Hewan, Universitas Udayana Bali. 13(3): 251 - 256.
Wijayantini, R., R, Cahyaningsih., dan A.N, Permatasari. 2018. Efektivitas Salep Ekstrak Etanol 70% Daun Pandan Wangi Terhadap Penyembuhan Luka Bakar Pada Mencit Putih Jantan. Jurnal Ilmiah Fitofarmaka. 8(1): 30-38.