Review Article: Use of Chitosan Nanoparticles as New Drug Delivery
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Abstract
Nanoparticle technology is beneficial as a drug carrier is high stability, and high carrier capacity. This carrier system can be designed to allow continuous drug release from the matrix, a polymer used for the formation of nanoparticles, one of which is chitosan. Chitosan is a polymeric substance that is used to form nanoparticles. The research method used is to review articles from several Google Scholar databases, ScienceDirect, pubmed. The advantage of chitosan is that processing it into nanoparticles allows chitosan to be used as a more effective delivery agent for pharmaceutical compounds or drugs.
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References
Agustin, Y. M. N., Meylina, L., & Sastyarina, Y. (2020). Uji Aktivitas Antioksidan Kombinasi Ekstrak Umbi Bawang Tiwai (Eleutherine bulbosa (Mill) Urb) dan Rimpang Kunyit(Curcuma domestica Val.). Proceeding of Mulawarman Pharma-ceuticals Conferences, 10(Mill), 151–155. https://doi.org/10.25026/mpc.v10i1.382
Amalia Riska Setyani, Enos Tangke Arung, & Yanti Puspita Sari. (2021). Phytochemical Screening, Antioxidant And Antibacterial Activity Of Ethanol Extract Of Bangle Fresh Root (Zingiber montanum). Jurnal Riset Teknologi Industri, 15(2), 415–427. https://repository.unmul.ac.id/bitstream/handle/123456789/11263/7436-32962-2-PB.pdf?sequence=1&isAllowed=y
Amaliah, D. (2018). Phytochemical Test and Antioxidant Activity on Methanol Extract of Rhizomes of Temu Hitam (Curcuma aeruginosa Roxb. Prosiding Seminar Nasional Kimia 2018 Kimia FMIPA UNMUL, 3(Iii), 23–26.
Arifin, M. F., Noviani, Y., Budiati, A., & Hidayanti, I. (2022). Formulasi Nanosuspensi Ekstrak Kering Rimpang Temulawak ( Curcuma xanthorrhiza Roxb .) Dengan Metode. 7(2), 126–135.
Asra, R., Azni, N. R., Rusdi, R., & Nessa, N. (2019). Uji Aktivitas Antioksidan Ekstrak Etanol Fraksi Heksan, Fraksi Etil Asetat dan Fraksi Air Daun Kapulaga (Elettaria cardamomum (L.) Maton). Journal of Pharmaceutical And Sciences, 2(1), 30–37. https://doi.org/10.36490/journal-jps.com.v2-i1.17
Cahyono, B., Prihatini, C. S., Suzer, M., & Bima, D. N. (2021). Aktivitas, Penentuan Senyawa, Antioksidan Lengkuas, Ekstrak Uv-vis, Menggunakan Hplc. Alchemy, Journal of Chemistry.
Djide, M. N. (2022). Djide. M. N. 3(1), 28–32.
Efiana, N. A., Nugroho, A. K., & Martien, R. (2013). Formulasi Nanopartikel Losartan dengan Pembawa Kitosan ( Formulation of Losartan Nanoparticles with Chitosan as a Carrier ). Jurnal Ilmu Kefarmasian Indonesia, 11(1), 7–12.
Erdoğan, Ü., & Erbaş, S. (2021). Phytochemical Profile And Antioxidant Activities of Zingiber officinale (Ginger) and Curcuma longa L.(Turmeric) Rhizomes. Bilge International Journal of Science and Technology Research, 1–6. https://doi.org/10.30516/bilgesci.991202
Harun, N., & Rahmawati, K. A. (2022). Aktivitas Antioksidan Perasan Kombinasi Ekstrak Rimpang Jahe, Kunyit, Lengkuas dan Kencur. Jurnal Kesehatan Bakti Tunas Husada: Jurnal Ilmu Keeawatan, Analis Kesehatan Dan Farmasi, 22(1), 8–14.
Iswandana, R., Jufri, M., & Effionora Anwar. (2013). Formulasi Nanopartikel Verapamil Hidroklorida dari Kitosan dan Natrium Tripolifosfat dengan Metode Gelasi Ionik. Jurnal Farmasi Indonesia, 6: 4(April 2014), 201–210.
Kiptiyah, S. Y., Harmayani, E., Santoso, U., & Supriyadi. (2021). The effect of blanching and extraction method on total phenolic content, total flavonoid content and antioxidant activity of Kencur (Kaempferia galanga. L) extract. IOP Conference Series: Earth and Environmental Science, 709(1). https://doi.org/10.1088/1755-1315/709/1/0-12025
Lallo, S., Lewerissa, A. C., Rafi’i, A., Usmar, U., Ismail, I., & Tayeb, R. (2022). Pengaruh Ketinggian Tempat Tumbuh Terhadap Aktivitas Antioksidan Dan Sitotoksik Ekstrak Rimpang Lengkuas (Alpinia galanga L.). Majalah Farmasi Dan Farmakologi, 23(3), 118–123. https://doi-.org/10.20956/mff.v23i3.9406
Mahral Effendi, S. (2019). Penentuan Kadar Senyawa Flavonoid Ekstrak Etanol Daun Kunyit ( Curcuma domestica Val ) Secara Spektrofotometri Uv-Vis. Herbal Medicine Journal, 2(2), 16–20.
Muhafidzah, Z., Dali, S., & Syarif, R. A. (2018). Aktivitas Antioksidan Fraksi Rimpang Kencur (Kaempferia rhizoma) Dengan Menggunakan Metode Peredaman 1,1 Diphenyl-2-picrylhydrazil (DPPH). Jurnal Ilmiah As-Syifaa, 10(1), 44–50. https:-//doi.org/10.33096/jifa.v10i1.326
Napsah, R., & Wahyuningsih, I. I. S. (2014). Preparasi Nanopartikel Kitosan-TPP/ Ekstrak Etanol Daging Buah Mahkota Dewa (Phalaeriamacrocarpa(Scheff)Boerl) dengan Metode Gelasi Ionik. Jurnal Farmasi Sains Dan Komunitas, 11(1), 7–12.
Nurcholis, W., & Bintang, M. (2017). Comparison between antioxidant activity and phenolics content of Curcuma zanthorrhiza and Curcuma aeruginosa Roxb. Indonesian Herb Journal, 2(1), 25–29.
Pertiwi, I., Zaman, N. N., Arifki, H. H., SIlalahi, K., H.P.P, W., & Wathoni, N. (2018). Kitosan Sebagai Eksperimen dalam Sistem Penghantaran Obat Baru. Farmaka, 16(03), 213–221.
Pratama, G., Yanuarti, R., Ilhamdy, A. F., & Suhana, M. P. (2019). Formulation of sunscreen cream from Eucheuma cottonii and Kaempferia galanga (zingiberaceae). IOP Conference Series: Earth and Enviro-nmental Science, 278(1). https://doi.org/-10.1088/1755-1315/278/1/012062.
Rissanti, I., Fachriyah, E., & Kusrini, D. (2014). Isolasi dan Identifikasi Senyawa Aktif dari Ekstrak Aseton Rimpang Bangle (Zingiber cassumunar Roxb.) sebagai Antioksidan. Jurnal Kimia Sains Dan Aplikasi, 17(3), 75–79. https://doi.org/10.14710/jksa.17.3.75-79
Rosidi, A., Khomsan, A., Setiawan, B., & Briawan, D. (2017). Potensi temulawak (c. Potensi Temulawak, 1995. https://jurnal.unimus.-ac.id/index.php/psn12012010/article/view/1219/1272
Siregar, G. A., Suwitono, M. R., & Sulastri, T. (2019). Determination of Antioxidant Activity and Organoleptic Score of Kencur ( Kaempferia galanga ) Fortified Bread. Jounal Mathematics and Science, 41–47.
Suena, N. M. D. S., Suradnyana, I. G. M., & Juanita, R. A. (2021). Formulasi Dan Uji Aktivitas Antioksidan Granul Effervescent Dari Kombinasi Ekstrak Kunyit Putih (Curcuma zedoaria) Dan Kunyit Kuning (Curcuma longa L.). Jurnal Ilmiah Medicamento, 7(1), 32–40. https://doi.org/-10.36733/medicamento.v7i1.1498
Sugara, B., Ramadhan, A. M., & Ibrahim, A. (2015). Uji Aktivitas Antioksidan Ekstrak Dan Fraksi Rimpang Temu Kunci (Boesenbergia pandurata) Dengan Metode 1,1-DifeniL-2-Pikrilhidrazil (DPPH). 22–26. https://doi.org/10.25026/mpc.v2i1.34
Sukmawati, A., Da’i, M., Zulinar, F., & Hanik, A. (2017). Profil Pelepasan Antikanker kombinasi Doksorubisin dan Analog Kurkumin dari Nanopartikel Kitosan. The 6th Research Colloquium 2017, 139–144.
Suparmajid, A. H., Sabang, S. M., & Ratman, R. (2017). Pengaruh Lama Penyimpanan Rimpang Kunyit (Curcuma domestica Vahl) Terhadap Daya Hambat Antioksidan. Jurnal Akademika Kimia, 5(1), 1. https://doi.org-/10.22487/j24775185.2016.v5.i1.7921
Zulvianti, P. N., Lestari, P. M., & Nining, N. (2022). Review Komposit Pati–Kitosan: Perannya dalam Berbagai Sistem Penghantaran Obat. Majalah Farmasetika, 7(1), 18. https://doi.org/10.24198/mfarmasetika.v7i1.36496