Main Article Content

Zahra Amalia Ristiana
Fauziah Fauziah
Siti Setianingsih

Page: 1887-1893

Abstract

Introduction: Hypertension is a chronic condition that requires long-term management through adherence to pharmacological therapy and a low-sodium diet. Both factors play an essential role in controlling blood pressure and preventing complications. Methods: This study employed a quantitative observational design with a cross-sectional approach conducted in February 2025 at four public health centers in Banyumas Regency. A total of 70 hypertensive patients enrolled in the PROLANIS program were selected using purposive sampling. Data were collected through interviews and health status documentation, then analyzed using the Chi-Square test and odds ratio (OR). Results: No significant relationship was found between pharmacological adherence and blood pressure (p systolic = 0.131; p diastolic = 0.434). Conversely, a significant association was observed between adherence to a low-sodium diet and blood pressure (p systolic = 0.000; p diastolic = 0.003). Odds ratio analysis indicated that patients adhering to a low-sodium diet were 1.86 times more likely to achieve controlled blood pressure compared to those who were non-adherent. Conclusion: Adherence to a low-sodium diet has a greater influence on blood pressure control than medication adherence. Therefore, educational interventions emphasizing the importance of dietary management and consistent medication intake should be optimized to improve the effectiveness of hypertension therapy in primary health care settings.

Downloads

Download data is not yet available.

Article Details

How to Cite
Ristiana, Z. A., Fauziah , F., & Setianingsih , S. (2025). Analysis of the Relationship Between Pharmacological Adherence and Low-Sodium Diet Compliance with Blood Pressure in Hypertensive Patients at Several Public Health Centers in Banyumas Regency. Journal of Pharmaceutical and Sciences, 8(3), 1887–1893. https://doi.org/10.36490/journal-jps.com.v8i3.967
Section
Original Articles

References

Lestari P, Yudanari Y, Saparwati M. Hubungan Aktifitas Fisik Dengan Kejadian Hipertensi Pada Usia Dewasa Di Puskesmas Kedu Kabupaten Temanggung. Jurnal Kesehatan Primer 2020;5:21–30.

Cheng HM, Lin HJ, Wang TD, Chen CH. Asian management of hypertension: Current status, home blood pressure, and specific concerns in Taiwan. J Clin Hypertens 2020;22:511–4. https://doi.org/10.1111/jch.13747. DOI: https://doi.org/10.1111/jch.13747

Dinas Kesehatan Jawa Tengah. Pelayanan Kesehatan Hipertensi Tahun 2023. Data Portal Jawa Tengah 2023. https://data.jatengprov.go.id/dataset/pelayanan-kesehatan-penderita-hipertensi-tahun-2023 (accessed September 10, 2024).

Anshari Z. Komplikasi Hipertensi Dalam Kaitannya Dengan Pengetahuan Pasien Terhadap Hipertensi Dan Upaya Pencegahannya. vol. 2. 2019. DOI: https://doi.org/10.36656/jpkm.v2i2.289

Ayu MS. Analisis Klasifikasi Hipertensi dan Gangguan Fungsi Kognitif pada Lanjut Usia. JUMANTIK (Jurnal Ilmiah Penelitian Kesehatan) 2021;6:131. https://doi.org/10.30829/jumantik.v6i2.8246. DOI: https://doi.org/10.30829/jumantik.v6i2.8246

Ulfa Azhar M, Islam Negeri Aluddin Makassar U, Penulis K. The Indonesian Journal of Health Promotion Open Access Terapi Non Farmakologi dalam Pengendalian Tekanan Darah Pada Pasien Hipertensi: Systematic Review Non Pharmacological Therapy in Blood Pressure Control in Hypertensive Patients: Systematic Review. MPPKI 2019;2. https://doi.org/10.31934/mppki.v2i3. DOI: https://doi.org/10.31934/mppki.v2i3.806

Febri Nilansari A, Munif Yasin N, Ayu Puspandari D. Gambaran Pola Penggunaan Obat Antihipertensi Pada Pasien Rawat Inap di RSUD Panembahan Senopati. Jurnal Ilmu Kefarmasian 2020;1. DOI: https://doi.org/10.31764/lf.v1i2.2577

Fauziah Y, Hariati Dongge S, Bina Husada Kendari P, Studi DIII Farmasi P, Kesehatan Kabupatan Konawe D. Analisis Tingkat Kepatuhan Pasien Hipertensi Dalam Minum Obat Di RSUD Kota Kendari Yulianti Fauziah Analisis Tingkat Kepatuhan Pasien Hipertensi Dalam Minum Obat Di RSUD Kota Kendari The Level Of Adherence To Taking Medication For Hypertensive Patients In The Public Hospital In Kendari City. vol. 8. 2019. DOI: https://doi.org/10.46356/wfarmasi.v8i2.115

Sinuraya RK, Destiani DP, Puspitasari IM, Diantini A. Medication Adherence among Hypertensive Patients in Primary Healthcare in Bandung City. Indonesian Journal of Clinical Pharmacy 2018;7:124–33. https://doi.org/10.15416/ijcp.2018.7.2.124. DOI: https://doi.org/10.15416/ijcp.2018.7.2.124

Liberty IA, Pariyana P, Roflin E, Waris L. Determinan Kepatuhan Berobat Pasien Hipertensi Pada Fasilitas Kesehatan Tingkat 1. Jurnal Penelitian Dan Pengembangan Pelayanan Kesehatan 2018;1:58–65. DOI: https://doi.org/10.22435/jpppk.v1i1.428

Pramana D. Penatalaksanaan Krisis Hipertensi. Jurnal Kedokteran 2020;2:91–6. DOI: https://doi.org/10.36679/kedokteran.v5i2.243

Juraschek SP, Woodward M, Sacks FM, Carey VJ, Miller ER, Appel LJ. Time Course of Change in Blood Pressure from Sodium Reduction and the DASH Diet. Hypertension 2017;70:923–9. https://doi.org/10.1161/HYPERTENSIONAHA.117.10017. DOI: https://doi.org/10.1161/HYPERTENSIONAHA.117.10017

Gumi VC, Larasanty LPF, Udayani NNW. Identifikasi Drug Related Problems Pada Penanganan Pasien Hipertensi di UPT Puskesmas Jembrana. Jurnal Farmasi Fakultas Matematika Dan Ilmu Pengetahuan Alam Universitas Udayana 2013.

Gupta DK, Lewis CE, Varady KA, Su YR, Madhur MS, Lackland DT, et al. Effect of Dietary Sodium on Blood Pressure: A Crossover Trial. JAMA 2023;330:2258–66. https://doi.org/10.1001/jama.2023.23651. DOI: https://doi.org/10.1001/jama.2023.23651

Netra Wirakhmi I, Purnawan I. Hubungan Kepatuhan Minum Obat Dengan Tekanan Darah Pada Penderita Hipertensi. vol. 12. 2021. DOI: https://doi.org/10.26751/jikk.v12i2.1079

Katzung BG. Basic & Clinical Pharmacology 14th Edition. New York: McGraw Hill Education; 2018.

James PA, Oparil S, Carter BL, Cushman WC, Dennison-Himmelfarb C, Handler J, et al. 2014 Evidence-based guideline for the management of high blood pressure in adults: Report from the panel members appointed to the Eighth Joint National Committee (JNC 8). JAMA 2014;311:507–20. https://doi.org/10.1001/jama.2013.284427. DOI: https://doi.org/10.1001/jama.2013.284427

Sudrajat A, Wulan T, Yardes N, Manurung S, Lusiana D, Wartonah W, et al. sudrajat 2024;4:104–12. DOI: https://doi.org/10.36082/jhcn.v4i2.1984

Nisa F, Husada Jombang Stik, Dwi Ana K. Hubungan kepatuhan diet rendah garam dengan tekanan darah pasien hipertensi di Klinik Intan Husada Jatirogo Tuban 2024.

Yunus MH, Kadir S, Lalu NAS. Hubungan Pola Konsumsi Garam Dengan Kejadian Hipertensi Pada Lansia Di Puskesmas Kota Tengah The Relationship Between Salt Consumption Patterns And The Incidence Of Hypertension In The Elderly At The Kota Tengah Health Center. Journal Health & Science : Gorontalo Journal Health and Science Community 2023. DOI: https://doi.org/10.35971/gojhes.v7i1.16279