Acute toxicity test of rattan cell extract (Daemonorop melanochaetes Bl.) on shrimp larva (Artemia Salina Leach) using the brine shrimp lethality test (BSLT) method

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Published: Feb 22, 2024
DOI: https://doi.org/10.36490/journal-jps.com.v7i1.463
Keywords:
Rattan Cell Extract, Acute Toxicity Test, Arthemia Salina Leach, Brine Shrimp Lethality Test

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Athaillah
Department of pharmacy, faculty of Health Sciences, Haji Sumatera Utara University, 20226, North Sumatra Province, Indonesia
Roqayyah Maulida Lubis
Department of pharmacy, faculty of Health Sciences, Haji Sumatera Utara University, 20226, North Sumatra Province, Indonesia
Putra Chandra
Department of pharmacy, faculty of Health Sciences, Haji Sumatera Utara University, 20226, North Sumatra Province, Indonesia
Aswan Pangondian
Department of pharmacy, faculty of Health Sciences, Haji Sumatera Utara University, 20226, North Sumatra Province, Indonesia
Robiatun Rambe
Department of pharmacy, faculty of Health Sciences, Haji Sumatera Utara University, 20226, North Sumatra Province, Indonesia

Page: 35-42

Abstract

Cell rattan is very popular because it has properties in treating malaria, diabetes and also has appetite-stimulating properties. The chemical content of rattan consists of flavonoids, alcohol, triterpenoids, saponins and glycosides. Flavonoids consist of 15 carbon atoms with a C6-C3-C6 structure. In plants, flavonoids are bound to sugars in the form of flavonoid glycosides and aglycones. Research methods include making rattan extract using the maceration method, phytochemical screening, toxicity activity testing using the BSLT (Brine Shrimp Lethality Test) method and determining the LC50 value based on the probit value. The research results show that rattan extract contains secondary metabolite compounds, including steroids/triterpenoids, saponins, flavonoids, glycosides and alkaloids. The results of the toxicity activity test showed that the LC50 value was 322 ppm and was included in the toxic category.

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How to Cite
Athaillah, A., Maulida Lubis, R., Chandra, P., Pangondian, A., & Rambe, R. (2024). Acute toxicity test of rattan cell extract (Daemonorop melanochaetes Bl.) on shrimp larva (Artemia Salina Leach) using the brine shrimp lethality test (BSLT) method. Journal of Pharmaceutical and Sciences, 7(1), 35–42. https://doi.org/10.36490/journal-jps.com.v7i1.463
Issue
JPS Volume 7 Nomor 1 (2024)
Section
Original Articles
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This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

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