Test The Effectivnessof Saga Leaf Extract (Abrus precatorius Linn) Ointmentfor Wound Treatmentin Rabbits (Oryctolagus Cuniculus)
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Robiatun Rambe, Ratih Paramitha, Ernawaty Ginting, Mita Yusmira Lestari Caniago (2021). Test The Effectivnessof Saga Leaf Extract (Abrus precatorius Linn) Ointmentfor Wound Treatmentin Rabbits (Oryctolagus Cuniculus). Journal of Pharmaceutical and Sciences, Vol. 4 No. 2 (2021): JPS Volume 4 Nomor 2 (2021). https://doi.org/10.36490/journal-jps.com.v5i1.56
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Abstract
Saga leaf (abrus precatorius Linn) contained flavonoids, tannins, triterpenoids are able to provide an antibacterial effect. The purpose of the study was to made a balm extract from saga leaf (abrus precatorius Linn)and test the effectiveness of ointments against the treatment of wounds on rabbit skin. Proces of balm extract from saga leaf has qualified the standard and tested on rabbit with 5 treatment groups, is injuries without negative control, positive control, saga leaf ointment 10%, 20% and 30%. All the rabbit were sliced 1,5 cm long and given 0,2 mL of saga leaf extract ointment. The wounds were applied with ointment three times daily. Observations was conducted everyday for 8 days. The result shows differences that the saga leaf formulation meets the ointment test requirement according to farmakope Indonesia edition III, wounds were narrowed, scabs were formed and then wounds were closed.
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