Study of Drug Interactions In Prescribing Diabetes Mellitus Patients In One of The Hospitals In Bandung City
Article Sidebar
Main Article Content
Page: 445-450
Abstract
Introduction: Drug interactions are events that occur if the use of drugs in a shared time. The drug interactions that occur can produce adverse or beneficial effects. Purpose: to determine the potential interaction of drugs given to outpatients with diabetes mellitus diagnosis in one of the hospitals. Method: the study was conducted using a descriptive analysis design, by collecting retrospective data using prescription documents for diabetic patients in outpatient pharmacy installations in hospitals in the city of Bandung. Results: the study showed that the Biguanida group was often used as much as 82.4% and the interaction of the use of Glimepirid with metformin as many as 25 cases (21.2%) with a moderate level of interaction. Conclusion: The antidiabetic drug that is often used is the Biguanida group with a frequent interaction is Glimepirid with metformin.
Downloads
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
References
American Diabetes Association, 2016. Erratum. Classification and diagnosis of diabetes. Sec. 2. In Standards of Medical Care in Diabetes–2016. Diabetes Care 2016; 39 (Suppl. 1): S13–S22. Diabetes care, 39(9), pp.1653-1653.
Foretz, M., Guigas, B. and Viollet, B., 2019. Understanding the glucoregulatory mechanisms of metformin in type 2 diabetes mellitus. Nature Reviews Endocrinology, 15(10), pp.569-589.
Hazra, M.,2022. A Clinical Pharmacological Study on the Prevailing Prescription Patterns Appraisal of the Combination Therapies of Metformin and Remogliflozin, Metformin and Sitagliptin, and Metformin and Gemigliptin, among Early Grade Type II Diabetic Patients.
May, M., and Schindler, C., 2016, Clinically and pharmacologically relevant interactions of antidiabetic drugs, Ther Adv Endocrinol Metab, Vol. 7(2), p. 69.
Pamu, S., Singh, T., Ravi, S. and Ranganayakulu, S.V., 2017. Evaluations of Drug-Drug Interactions in Hypertensive Patients in Secondary Care Hospital. IOSR Journal of Pharmacy and Biological Sciences, 12(02), pp.45-50.
PERKENI. 2021. Konsensus Pengelolaan dan Pencegahan Diabetes Melitus tipe 2 di Indonesia 2021. Pengurus Besar Perkumpulan Endokrinologi Indonesia. PB PERKENI.
Poluan, O.A., Wiyono, W.I. and Yamlean, P.V., 2020. Identifikasi potensi interaksi obat pada pasien diabetes melitus tipe 2 rawat inap di rumah sakit gunung maria tomohon periode januari–mei 2018. Pharmacon, 9(1), pp.38-46.
Rahman, H. and Octavia, T.A., 2019. Kajian Interaksi Obat Metformin pada Pasien Diabetes Mellitus. Jurnal Farmasetis, 8(2), pp.55-58.
Rethinam, A., 2019. A Prospective Study on Prescribing Patterns of Anti-Diabetic Drugs for Patients With Type-II Diabetes Mellitus at a Tertiary Care Hospital (Doctoral dissertation, JKK Nattraja College of Pharmacy, Kumarapalayam).
Sankar, V. et al. (2015) ‘Serious Drug-Drug Interactions in the Prescriptions of Diabetic Patients’, Medical Sciences, 3(4), pp. 93–103.
Safitri, B., 2017. Kajian interaksi obat pasien diabetes mellitus tipe 2 ditinjau dari outcome terapi di rumah sakit angkatan laut dr. mitohardjo (Bachelor's thesis, UIN Syarif Hidayatullah Jakarta: Fakultas Kedokteran dan Ilmu Kesehatan, 2017).
Singleton, J. dkk (2017) ‘Analysis of a CommunityPharmacy Intervention to Improve Low Adherence Rates to Oral Diabetes Medications’, Pharmacy, 5(4), p. 58.
Sucipto, A. and Rosa, E. M. (2014) ‘Efektivitas Konseling DM dalam Meningkatkan Kepatuhan danPengendalian Gula Darah pada Diabetes Melitus Tipe 2’, Muhammadiyah Journal of Nursing, 1(2), pp. 9–20.
Talbert, R. L. and Dipiro, J. T. (2014) PharmacotherapyA Pathophysiologic Approach. 9th edn. Newyork: TheMcGraw-Hill Companies Inc.
Yang, H. et al. (2017) ‘Association between Knowledge- Attitude-Practices and Control of Blood Glucose, BloodPressure, and Blood Lipids in Patients with Type 2Diabetes in Shanghai, China: A Cross-Sectional Study’, Journal of Diabetes Research. Hindawi, 2017, pp. 1–9.
WHO Global report. 2016. Global report on diabetes. 6-86