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Astrid Yudhit
Sondang Pintauli
Ellyza Herda
Aminah Dalimunthe

Page: 1239-1245

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Latar Belakang: Proses pengeringan dalam pembuatan simplisia mempengaruhi mutu, kandungan senyawa kimia, dan mineral bahan herbal. Kulit pisang Barangan (Musa acuminata Colla) berpotensi sebagai agen dental preventif karena kandungan fitokimia dan mineralnya. Tujuan: Penelitian ini bertujuan untuk menganalisis mutu simplisia (kadar air dan kadar abu total) serta komposisi senyawa kimia dan mineral kulit pisang Barangan yang dikeringkan dengan dua metode berbeda. Metode: Penelitian ini merupakan studi analisis kualitatif. Kulit pisang Barangan yang telah dibersihkan dan dicacah dibagi menjadi dua kelompok: pengeringan oven (60°C, 12 jam) dan pengeringan beku (freeze drying; -65°C selama 4 jam dilanjutkan 48 jam). Simplisia dihaluskan dengan ball mill (500 rpm, 6 jam). Kadar air diuji dengan metode toluena, kadar abu total dengan pemanasan 800°C. Identifikasi senyawa kimia dan mineral dilakukan menggunakan GC-MS dan XRF. Hasil: Kadar air kelompok oven (OD) sebesar 9,23% dan kelompok freeze drying (FD) sebesar 7,11%; kadar abu total masing-masing 10,83% dan 10,60%. Keduanya memenuhi standar Farmakope Herbal Indonesia (kadar air <10%, kadar abu total <15%). Identifikasi GC-MS menunjukkan kelompok FD memiliki variasi senyawa kimia lebih banyak (12 komponen) dibandingkan OD (7 komponen). Kandungan mineral tertinggi pada kedua kelompok adalah kalium (K), dengan magnesium (Mg) lebih tinggi pada OD (15,32%) dibandingkan FD (9,95%). Kesimpulan: Metode pengeringan berpengaruh terhadap mutu dan komposisi kulit pisang Barangan. Freeze drying menghasilkan kadar air lebih rendah dan variasi fitokimia lebih banyak, sedangkan pengeringan oven cenderung mempertahankan mineral lebih tinggi pada beberapa unsur. Simplisia kulit pisang Barangan dari kedua metode berpotensi dikembangkan sebagai bahan dental preventif.

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Cara Mengutip
Yudhit, A., Pintauli, S., Herda, E., & Dalimunthe, A. (2026). Mutu Simplisia dan Komposisi Kulit Pisang Barangan (M. acuminata Colla) Sebagai Bahan Dental Preventif Dengan Metode Pengeringan Berbeda. Journal of Pharmaceutical and Sciences, 9(2), 1239–1245. https://doi.org/10.36490/journal-jps.com.v9i2.1391
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Referensi

Lee YJ, Kim MS. Advances in drug-loaded microspheres for targeted, controlled, and sustained drug delivery: Potential, applications, and future directions. Biomed Pharmacother 2025;189:118244. https://doi.org/10.1016/j.biopha.2025.118244. DOI: https://doi.org/10.1016/j.biopha.2025.118244

Karnjana K, Jewboonchu J, Niyomtham N, Tangngamsakul P, Bunluepuech K, Goodla L, et al. The potency of herbal extracts and its green synthesized nanoparticle formulation as antibacterial agents against Streptococcus mutans associated biofilms. Biotechnol Reports 2023;37:e00777. https://doi.org/10.1016/j.btre.2022.e00777. DOI: https://doi.org/10.1016/j.btre.2022.e00777

Cheng X, Yan H, Pang S, Ya M, Qiu F, Qin P, et al. Liposomes as Multifunctional Nano-Carriers for Medicinal Natural Products. Front Chem 2022;10:1–20. https://doi.org/10.3389/fchem.2022.963004. DOI: https://doi.org/10.3389/fchem.2022.963004

Arulanandraj N, Dhivya S, Gopal V. A review on Herbal Nanoparticles. Pharmatutor 2018;6:32. https://doi.org/10.29161/pt.v6.i5.2018.32. DOI: https://doi.org/10.29161/PT.v6.i5.2018.32

Chakraborty K, Shivakumar A, Ramachandran S. Nano-technology in herbal medicines: A review. Int J Herb Med 2016;4:21–7. https://doi.org/10.22271/flora.2016.v4.i3.05. DOI: https://doi.org/10.22271/flora.2016.v4.i3.05

Nurhaslina CR, Andi Bacho S, Mustapa AN. Review on drying methods for herbal plants. Mater Today Proc 2022;63:S122–39. https://doi.org/10.1016/j.matpr.2022.02.052. DOI: https://doi.org/10.1016/j.matpr.2022.02.052

World Health Organization. Quality control methods for medicinal plant materials World Health Organization Geneva. Who 1998.

Direktorat Jenderal Kefarmasian dan Alat Kesehatan. Farmakope Herbal Indonesia. II. Jakarta: Kementerian Kesehatan RI; 2017.

Belwal T, Cravotto C, Prieto MA, Venskutonis PR, Daglia M, Devkota HP, et al. Effects of different drying techniques on the quality and bioactive compounds of plant-based products: a critical review on current trends. Dry Technol 2022;40:1539–61. https://doi.org/10.1080/07373937.2022.2068028. DOI: https://doi.org/10.1080/07373937.2022.2068028

Nakra S, Tripathy S, Srivastav PP. Drying as a preservation strategy for medicinal plants: Physicochemical and functional outcomes for food and human health. Phytomedicine Plus 2025;5:100762. https://doi.org/10.1016/j.phyplu.2025.100762. DOI: https://doi.org/10.1016/j.phyplu.2025.100762

Manalu LP, Adinegoro H, Yustiningsih N, Astuti, Luthfiyanti R, Maisaroh, et al. Impact of Drying Methods on Bioactive Compounds and Antioxidant Properties of Kalanchoe ceratophylla. Scientifica (Cairo) 2025;2025. https://doi.org/10.1155/sci5/7146758. DOI: https://doi.org/10.1155/sci5/7146758

Oliveira-Alves SC, Andrade F, Prazeres I, Silva AB, Capelo J, Duarte B, et al. Impact of drying processes on the nutritional composition, volatile profile, phytochemical content and bioactivity of salicornia ramosissima j. Woods. Antioxidants 2021;10:1–33. https://doi.org/10.3390/antiox10081312. DOI: https://doi.org/10.3390/antiox10081312

Z UBA, M H. A review of the applications of different drying methods of banana flour preparation. Food Res 2023;7:297–304. https://doi.org/https://doi.org/10.26656/fr.2017.7(1).651. DOI: https://doi.org/10.26656/fr.2017.7(1).651

Mphahlele RR, Fawole OA, Makunga NP, Opara UL. Effect of drying on the bioactive compounds, antioxidant, antibacterial and antityrosinase activities of pomegranate peel. BMC Complement Altern Med 2016;16:1–12. https://doi.org/10.1186/s12906-016-1132-y. DOI: https://doi.org/10.1186/s12906-016-1132-y

Mohd Zaini H, Roslan J, Saallah S, Munsu E, Sulaiman NS, Pindi W. Banana peels as a bioactive ingredient and its potential application in the food industry. J Funct Foods 2022;92:105054. https://doi.org/10.1016/j.jff.2022.105054. DOI: https://doi.org/10.1016/j.jff.2022.105054

Evbuomwan L, Bright Jacob I, Onodje GO, Patrick CE. Evaluating The Antibacterial Activity OF Musa acuminata (Banana) Fruit Peels Against Multidrug Resistant Bacterial Isolates. Int J Nov Res Life Sci 2018;5:26–31.

Anjum S, Sundaram S. Comparative Analysis of Antibacterial Activity of Banana Peel at Different Stages of Ripening. Int J Pharm Sci Drug Res 2023;15:1–11. https://doi.org/10.25004/ijpsdr.2023.150101. DOI: https://doi.org/10.25004/IJPSDR.2023.150101

Likittrakulwong W, Chanburee S, Kitpot T, Ninjiaranai P, Pongpamorn P. Phytochemical Properties, In Vitro Antimicrobial, and Bioactive Compounds of Banana Peel Extractions Using GC-MS. Nat Life Sci Commun 2023;22. https://doi.org/10.12982/NLSC.2023.021. DOI: https://doi.org/10.12982/NLSC.2023.021

Oyeyinka BO, Afolayan AJ. Comparative evaluation of the nutritive, mineral, and antinutritive composition of musa sinensis l. (banana) and musa paradisiaca l. (plantain) fruit compartments. Plants 2019;8. https://doi.org/10.3390/plants8120598. DOI: https://doi.org/10.3390/plants8120598

Sipahutar A, Pintauli S, Dalimunthe A. Efek Pasta Nanopartikel Kulit Pisang Barangan (Musa Paradisiaca Colla) Terhadap Permukaan Enamel Gigi Menggunakan Scanning Electron Microscopy 2024;16:85–92. DOI: https://doi.org/10.24815/cdj.v16i2.40140

Bashir S, Hussain SZ, Jan N, Naseer B, Zargar IA, Murtaza I, et al. Structural integrity, bioactive components, and physico-chemical characteristics of Kashmiri saffron (Crocus sativus L.) as affected by different drying techniques. Food Chem 2025;476. https://doi.org/10.1016/j.foodchem.2025.143511. DOI: https://doi.org/10.1016/j.foodchem.2025.143511

Nowak D, Jakubczyk E. The freeze-drying of foods⇔the characteristic of the process course and the effect of its parameters on the physical properties of food materials. Foods 2020;9. https://doi.org/10.3390/foods9101488. DOI: https://doi.org/10.3390/foods9101488

Bryan E, Ferrer-González E, Sagong HY, Fujita J, Mark L, Kaul M, et al. Structural and Antibacterial Characterization of a New Benzamide FtsZ Inhibitor with Superior Bactericidal Activity and In Vivo Efficacy Against Multidrug-Resistant Staphylococcus aureus. ACS Chem Biol 2023;18:629–42. https://doi.org/10.1021/acschembio.2c00934. DOI: https://doi.org/10.1021/acschembio.2c00934

Wrońska N, Szlaur M, Zawadzka K, Lisowska K. The Synergistic Effect of Triterpenoids and Flavonoids— New Approaches for Treating Bacterial Infections? Molecules 2022;27. https://doi.org/10.3390/molecules27030847. DOI: https://doi.org/10.3390/molecules27030847

Tzimas K, Antoniadou M, Varzakas T, Voidarou C. Plant-Derived Compounds: A Promising Tool for Dental Caries Prevention. Curr Issues Mol Biol 2024;46:5257–90. https://doi.org/10.3390/cimb46060315. DOI: https://doi.org/10.3390/cimb46060315