Potensi Antimikroba Ekstrak Infus Daun Pedada (Sonneratia caseolaris L) Mandeh, Sumatera Barat
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Meningkatnya resistensi antibiotik merupakan ancaman serius bagi kesehatan global dan mendorong pencarian sumber antimikroba alternatif dari bahan alam. Mangrove pedada (Sonneratia caseolaris L.) yang banyak ditemukan di kawasan pesisir Mandeh, Sumatera Barat, secara tradisional dimanfaatkan sebagai tanaman obat. Penelitian ini bertujuan untuk mengevaluasi potensi antimikroba ekstrak infus daun Sonneratia caseolaris serta pengaruh variasi waktu pemanasan terhadap aktivitasnya. Ekstrak infus daun dibuat menggunakan pelarut air mendidih dengan variasi waktu pemanasan 10, 15, dan 30 menit. Aktivitas antimikroba diuji terhadap Escherichia coli, Staphylococcus aureus, dan Candida albicans menggunakan metode difusi cakram. Hasil penelitian menunjukkan bahwa seluruh ekstrak infus memiliki aktivitas antimikroba dengan tingkat daya hambat yang bervariasi. Waktu pemanasan 10 menit menghasilkan aktivitas antimikroba tertinggi dengan diameter zona hambat masing-masing sebesar 10,5 mm terhadap E. coli, 10 mm terhadap S. aureus, dan 10 mm terhadap C. albicans. Hasil ini menunjukkan bahwa ekstrak infus daun Sonneratia caseolaris berpotensi sebagai sumber antimikroba alami, dengan waktu pemanasan optimal selama 10 menit.
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