Uji Iritasi Kulit Sediaan Sunscreen Spray yang Mengandung Ekstrak Bunga Telang (Clitoria ternatea) dengan Metode Patch Test
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Latar Belakang: Bunga telang (Clitoria ternatea) mengandung antosianin tinggi dengan aktivitas antioksidan yang kuat, sehingga berpotensi sebagai bahan alami dalam sediaan tabir surya. Namun, keamanan terhadap kulit dari sediaan sunscreen spray yang mengandung ekstrak ini perlu dievaluasi sebelum aplikasi kosmetik. Tujuan: Penelitian ini bertujuan untuk mengevaluasi potensi iritasi kulit dari sediaan sunscreen spray yang mengandung ekstrak bunga telang menggunakan metode patch test. Metode: Uji patch test dilakukan pada 15 ekor tikus Wistar jantan. Bahan uji berupa sediaan sunscreen spray dengan konsentrasi ekstrak bunga telang 1% (F1), 2% (F2), dan 3% (F3). Formulasi dasar tanpa ekstrak (F0) digunakan sebagai kontrol negatif dan natrium lauril sulfat sebagai kontrol positif. Skor eritema dan edema diamati pada 24, 48, dan 72 jam setelah aplikasi. Hasil: Skor rata-rata eritema dan edema pada formulasi F1, F2, dan F3 adalah 0,0 ± 0, yang menunjukkan tidak terjadi tanda-tanda iritasi kulit pada semua kelompok uji. Kelompok kontrol positif menunjukkan eritema ringan (skor 2,33 ± 0,5), yang mengonfirmasi validitas metode uji. Kesimpulan: Sediaan sunscreen spray yang mengandung ekstrak bunga telang pada konsentrasi 1%, 2%, dan 3% tidak menyebabkan iritasi kulit pada tikus Wistar jantan berdasarkan metode patch test. Hasil ini mendukung potensi ekstrak bunga telang sebagai bahan alami yang aman untuk produk tabir surya.
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