Formulation and Physical Quality Test of Antiperspirant Cream from White Turmeric Extract (Curcuma zedoaria (Berg.) Roscoe)
Article Sidebar
Main Article Content
Page: 1236-1250
Abstract
Background: Curcuma zedoaria (Berg.) Roscoe, commonly known as white turmeric, is a plant from the Zingiberaceae family that contains bioactive compounds such as curcumin, flavonoids, alkaloids, saponins, and tannins. These compounds have potential as natural antiperspirants due to their astringent and antimicrobial properties, which can reduce sweat production and prevent body odor. The use of synthetic antiperspirants containing aluminum chloride often causes skin irritation, highlighting the need for safer, natural alternatives. Objective: This study aims to formulate an antiperspirant cream using white turmeric (Curcuma zedoaria (Berg.) Roscoe) extract with good physical quality and to evaluate the effectiveness of various concentrations in inhibiting sweat production. Methods: This experimental study involved extracting white turmeric using 96% ethanol through maceration, followed by concentration with a rotary evaporator. The antiperspirant cream was formulated with varying extract concentrations. Physical quality evaluations included organoleptic testing, homogeneity, pH, stability, viscosity, adhesion, spreadability, cream type, as well as irritation and antiperspirant tests on volunteers. Results: Phytochemical screening showed that the white turmeric extract contains alkaloids, flavonoids, saponins, and tannins. The cream with a 17.5% extract concentration demonstrated the highest antiperspirant effectiveness compared to 7.5% and 12.5% concentrations. All formulations met physical quality standards, including pH (4.5–6.5), viscosity (2,700–23,020 cP), and 14-day stability without significant changes. Conclusion: The white turmeric-based antiperspirant cream met physical quality standards and exhibited significant antiperspirant effects, particularly at a 17.5% concentration. This study demonstrates the potential of white turmeric as a safe and effective natural active ingredient in antiperspirant formulations.
Downloads
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
References
Referensi
Cahyanta AN, Istriningsih E, Zen DA, Gautama TS. Pengaruh Variasi Konsentrasi Ekstrak Daun Teh (Camellia sinensis L) Terhadap Sifat Fisik Deodorant Stick. Bhamada J Ilmu Dan Teknol Kesehat 2019;10:11–20. DOI: https://doi.org/10.36308/jik.v10i1.128
Ervianingsih N, Razak A. Formulasi Sediaan Deodorant Lotion Dari Minyak Atsiri Nilam (Pogostemon cablin Benth). J Fenom Kesehat 2019;2:188–96.
Silalahi M. Curcuma Zedoaria (Christm.) Roscoe (Benefits and Bioactivity). Eureka Herba Indones 2020;1:44–52. https://doi.org/10.37275/ehi.v1i2.10. DOI: https://doi.org/10.37275/ehi.v1i2.10
Mozartha M, Silvia P, Sujatmiko B. Perbandingan Aktivitas Antibakteri Ekstrak Curcuma Zedoaria Dan Bahan Irigasi Natrium Hipoklorit 2.5% Terhadap Enterococcus Faecalis. J Mater Kedokt Gigi 2019;8:22. https://doi.org/10.32793/jmkg.v8i1.330. DOI: https://doi.org/10.32793/jmkg.v8i1.330
Grandis L, Chiuman L, Wijaya LL, Indriani V, Lister G. Uji Efektivitas Ekstrak Rimpang Kunyit Putih (Curcuma Zedoaria) Terhadap Pertumbuhan Jamur (Pityrosporum Ovale) Dan (Microsporum Canis). (Jurnal Ilm Mhs Kesehat Masyarakat) 2020;5. https://doi.org/10.37887/jimkesmas.v5i1.10516. DOI: https://doi.org/10.37887/jimkesmas.v5i1.10516
Sinaga E, Supartiningsih S, Maimunah S, Jayadi N. Formulasi Sediaan Krim Deodorant Ekstrak Etanol Daun Beluntas (Plucea indica Less.) Sebagai Pencegah Bau Badan. J FARMANESIA 2020;7:23–30. https://doi.org/10.51544/jf.v7i1.2762. DOI: https://doi.org/10.51544/jf.v7i1.2762
Nurhaini R, Arrosyid M, Putri H. Formulasi dan uji aktivitas antibakteri deodoran krim dengan variasi minyak atsiri bunga kenanga (Cananga odorata var. Macrophylla) sebagai penghilang bau badan. CERATA J Ilmu Farm 2022;13:26–30. DOI: https://doi.org/10.61902/cerata.v13i1.453
Nurhanifah I, Sukmawati A. Formulasi dan Uji Aktivitas Antibakteri Sediaan Krim Minyak Atsiri Daun Kemangi (Ocimum basilicum L.) Sebagai Deodoran terhadap Staphylococcus epidermidis. Pros. Univ. Res. Colloq., 2019, p. 167–75.
Depkes RI. Cara Pembuatan Simplisia. 1985.
Depkes RI J. Farmakope Indonesia Edisi III 1979.
Dirjen POM. Farmakope Indonesia Edisi. IV. Jakarta: Depkes RI; 1995.
Cahyani N, Susiarni J, Dewi KCS, Melyandari NLP, Putra KWA, Swastini DA. Karakteristik dan skrining fitokimia ekstrak etanol 70% batang Kepuh (Sterculia foetida L.). J Kim (Journal Chem 2019;13:22–8. DOI: https://doi.org/10.24843/JCHEM.2019.v13.i01.p04
Sihotang LIR, Dalimunthe GI, Lubis MS, Yuniarti R. Formulasi eyeshadow kombinasi umbi bit (Beta vulgaris L.) dan rimpang kunyit (Curcuma longa L.) dalam perbandingan ekstrak dan nanoekstrak. J Pharm Sci 2024:776–95. DOI: https://doi.org/10.36490/journal-jps.com.v7i4.723
Zannah M, Dalimunthe GI, Lubis MS, Yuniarti R. Drug Formulasi paper soap ekstrak etanol dedak padi (Oryza sativa L.) dan uji aktivitas antibakteri terhadap bakteri Escherichia coli dan Staphylococcus aureus. J Pharm Sci 2025:324–45. DOI: https://doi.org/10.36490/journal-jps.com.v8i1.229
Depkes RI. Farmakope Indonesia Edisi 3. Edisi 3. Jakarta: Departemen Kesehatan RI; 1979.
Febriyossa A, Rahayuningsih N. Uji Daya Hambat Perasan Rimpang Jahe Putih, Kunyit Dan Temulawak Terhadap Pertumbuhan Bakteri Staphylococcus Aureus. J Syntax Admiration 2021;2:1–6. https://doi.org/10.46799/jhs.v2i1.97. DOI: https://doi.org/10.46799/jhs.v2i1.97
Mahmudah R, Hasanah RN, Aspadiah V, Sida NA, Hikmah N, Akib NI, et al. Formulasi dan Evaluasi Krim Kombinasi Tawas dan Ekstrak Lidah Buaya (Aloe vera) sebagai Antiperspirant. Lansau J Ilmu Kefarmasian 2023;1:153–61. DOI: https://doi.org/10.33772/lansau.v1i2.19
Mayangsari FD, Pratiwi ED, Sari DIK, Nurwanda FSA. Formulasi Krim Deodoran-Anti perspiran Alami yang Mengandung Kombinasi Minyak Atsiri sebagai Pengaroma. Maj Farmasetika 2023;9:91–103. DOI: https://doi.org/10.24198/mfarmasetika.v9i1.49912
Sembiring P. Formulasi Dan Uji Ektivitas Antibakteri Sediaan Lotion Ekstrak Etanol Daun Sawao Terhadap Bakteri Stapylococcuc aureus dan Escherchia coli. J Penelit Farm Herb 2022;4:20–8. DOI: https://doi.org/10.36656/jpfh.v4i2.853
Sembiring NB, Faradina A. Formulasi Sediaan Krim Ekstrak Etanol Jahe Merah (Zingiber Officinalis var. Rubrum) Sebagai Antidiabetic Foot n.d.
RI D. Parameter standar umum ekstrak tumbuhan obat : Jakarta Departemen Kesehatan Republik Indonesia. Ed IV 2000.