Main Article Content

Vista Kamilania
Patihul Husni

Page: 1935-1940

Abstract

Cosmetics are products used to improve the appearance of the outer body. Cosmetics are inseparable from dyes. One dye that is often misused in cosmetic products is Rhodamine B. Rhodamine B can cause liver damage and irritation of the respiratory tract and is carcinogenic. This review article aims to provide information on the use of analytical techniques to identify cosmetic products containing rhodamine B. The method used is a literature review by searching research journals with a period of 2013-2023 on Science Direct and Google Scholar using the keywords "identification of k10 red dye in cosmetics", "rhodamine B analysis in cosmetics," and "k10 red dye analysis method in cosmetics". Based on the literature review that has been carried out, identifying the content of rhodamine B dye can be done with various analysis techniques including Thin Layer Chromatography (TLC), High Performance Liquid Chromatography (HPLC), UV Vis Spectrophotometry, Ultra Performance Liquid Chromatography Tandem Mass Spectrometric (UPLC-MS), and rapid test kit. Qualitative analysis of rhodamine B content in cosmetics can be done with KLT and a rapid test kit. Quantitative analysis can be done using UV Vis, KCKT, and UPLC MS spectrophotometry methods.

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How to Cite
Kamilania, V., & Husni, P. (2023). Article review: analytical methods in testing the content of red K10 (Rhodamine B) dye in cosmetics. Journal of Pharmaceutical and Sciences, 6(4), 1935–1940. https://doi.org/10.36490/journal-jps.com.v6i4.349
Section
Review Article

References

Afriyeni, H & Utari, W.N. (2016). Identifikasi Zat Warna Rhodamin B Pada Lipstik Berwarna Merah yang Beredar di Pasar Raya Padang. Jurnal Farmasi Higea. 8(1).

Agoes, G. (2015). Sediaan Kosmetik. 1st ed. Bandung: ITB Press.

BPOM RI. (2014). Penggunaan Rhodamin B pada Kosmetik. Jakarta: Badan Pengawas Obat dan Makanan Republik Indonesia.

BPOM RI. (2019). Peraturan Badan Pengawas Obat Dan Makanan Nomor 20 Tahun 2019 Tentang Kemasan Pangan. Jakarta: BPOM RI.

Chawla, G., & Ranjan, C. (2016). Principle, Instrumentation, And Applications Of UPLC: A Novel Technique of Liquid Chromatography. Open Chemistry Journal. 3(1): 1-16.

Dominika, N., Hasyim. (2019). Perlindungan Hukum Terhadap Konsumen Atas Penjualan Kosmetik Berbahaya di Indonesia: Suatu Pendekatan Kepustakaan. Niagawan. 8(1): 60-67.

Fajriani, N., Kurniawan, H., Nugraha, F. (2022). Identifikasi Pewarna Rhodamin B pada Lipstik dengan metode Kromatografi Lapis Tipis (KLT). Journal Syifa Sciences and Clinical Research. 4(3): 671-678.

Fauziyah, R., Hariningsih. Y., Maritha V. (2021). Analisis Rhodamin-B Pada Lip Cream Yang Beredar di Aplikasi Belanja Online Secara Kromatografi Cair Kinerja Tinggi. Duta Pharma Journal. 1(1): 12-20.

Hasanah, A.N., Musfiroh, I., Saptarini, N.M., Rahayu, D. (2014). Identifikasi Rhodamin B pada Produk Pangan dan Kosmetik yang Berdear di Bandung. Jurnal Ilmu Kefarmasian Indonesia. 12(1): 104-109.

Kambira, P.F.A., Notario, D., Gunawan, U., Dhamayanti, S., Ningrum, R.W.K., Ambarita, S.G.O., Polin, G. (2020). Combination UV-Vis Spectroscopy and Partial Least Square for Detecting Adulteration Paracetamol and Piroxicam in Traditional Medicines. Journal of Pharmaceutical Sciences and Community. 17(1): 41–50.

Kemenkes RI. (2014). Farmakope Indonesia. Edisi V. Jakarta: Kementerian Kesehatan Republik Indonesia.

Khan, M.R., Khan, J.M., Alqadami, A.A. (2018). A Simple Solvent Extraction and Ultra-Performance Liquid Chromatography-Tandem Mass Spectrometric Method for The Identification And Quantification of Rhodamine B in Commercial Lip Balm Samples. Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy. 206: 72–77.

Komarudin, D., Fauziah, S., Pramintari, R. (2019). Analisis Rhodamin B pada Sediaan Lipstik dan Perona Mata secara Kromatografi Cair Kinerja Tinggi. Jurnal Ilmiah Kesehatan. 18(3): 88-92.

Mamoto, L.V., Citraningtyas, F.G. (2013). Analisis Rhodamin B Pada Lipstik yang Beredar di Pasar Kota Manado. Jurnal Ilmiah Farmasi. 2(2): 61-66.

Nafiq, U., Yuniarto, P.F., Sulistyowati, Y. (2020). Analisis Kandungan Rhodamin B Pada Eyeshadow yang Beredar di Daerah Kediri dan Nganjuk. Jurnal Mahasiwa Kesehatan. 1(2): 131-139.

Nanda, E.V., Darayani, A.E. (2018). Analisis Rhodamin B pada Lipstik yang Beredar Via Online ShopMenggunakan Metode Kromatografi Lapis Tipis (KLT) dan Spektrofotometri UV-Vis. Sainstech Farma. 11(2): 17-20.

Novhadi, T.T., Elmatris, Indra, B. (2021). Identifikasi Kandungan Rhodamin B pada Perona Pipi yang Terdaftar dan Tidak Terdaftar dalam BPOM dari Produk yang Beredar di Kecamatan Lubuk Begalung Kota Padang. Jurnal Ilmu Kesehatan Indonesia. 2(3): 122-126.

Rawat, B., Garg, A.P. (2021). Characterization of Phytochemicals Isolated from Cucurbita Pepo Seeds Using UV–Vis and FTIR Spectroscopy. Plant Archives. 21(1): 892-899.

Rubiyanto, D. (2017). Metode Kromatografi Prinsip Dasar, Praktikum dan Pendekatan Pembelajaran Kromatografi. Yogyakarta: Deepublish.

Safitri, Y.A., Indrawan, I.W.A., dan Winarsih, S. (2015). Rhodamine B Induces Oxidative Stress and Cervical Epithelial Cell Proliferation in The Uterus. Toxicology Reports. 2: 1434-1436.

Satiyarti, R.B., Anggaraini, N., Sugiharta, I. (2021). Deteksi Rhodamin B pada Perona Pipi Murah di Kota Bandar Lampung. Jurnal Kartika Kimia. 4(1): 38-41.

Taleuzzaman, M., Ali, S., Gilani, S.J., Imam, S.S., Hafeez, A. (2015). Ultra Performance Liquid Chromatography (UPLC) - A Review. Austin J Anal Pharm Chem. 2(6): 1056.

Taupik, M., Mustapa, M.A., Gonibala, S. (2021). Analisis Kadar Rhodamin B pada Blush-On Menggunakan Metode Spektrofotometri UV-Vis. Indonesian Journal of Pharmaceutical Education. 1(2): 119-126.

Tumanduk, R., Massi, M.N., Agus, R., Hamid, F. (2023). Analisis Residu Amoksisilin pada Hepar dan Ventrikulus Ayam Petelur di Pasar Tradisional Makassar. Jurnal Ilmu Alam dan Lingkungan. 14(2): 20-28.

Wani, T.A. (2013). Highly Sensitive Ultra-Performance Liquid Chromatography–Tandem Mass Spectrometry Method for The Determination of Abiraterone in Human Plasma. Analytical Methods. 5: 3693–3699.

Warono, D., Syamsudin. (2013). Unjuk Kerja Spektrofotometer Untuk Analisa Zat Aktif Ketoprofen. Konversi. 2(2): 57–65.

Yulianti, I. (2017). Tanggung jawab sosial terhadap pemakaian pewarna sintetik Rhodamin B pada masyarakat. Tedc. 11(3):229–35.