Main Article Content

Astrid Yudhit
Sondang Pintauli
Ellyza Herda
Aminah Dalimunthe

Page: 1239-1245

Abstract

Background: The drying process in the preparation of herbal material affects the quality, chemical compound content, and mineral composition of herbal ingredients. Barangan banana peel (Musa acuminata Colla) has potential as a preventive dental agent due to its phytochemical and mineral content. Objective: This study aimed to analyze the simplicia quality (moisture content and total ash content) as well as the chemical compound and mineral composition of Barangan banana peel dried using two different methods. Methods: This was a qualitative analytical study. Cleaned and chopped Barangan banana peels were divided into two groups: oven-dried (OD; 60°C for 12 hours) and freeze-dried (FD; -65°C for 4 hours followed by 48 hours of freeze drying). The simplicia was ground using a ball mill (500 rpm for 6 hours). Moisture content was determined using the toluene method, while total ash content was measured by heating at 800°C. Identification of chemical compounds and minerals was performed using GC-MS and XRF, respectively. Results: Moisture content of the OD group was 9.23% and of the FD group was 7.11%; total ash content was 10.83% and 10.60%, respectively. Both met the standards of the Indonesian Herbal Pharmacopoeia (moisture content <10%, total ash content <15%). GC-MS identification revealed that the FD group exhibited a greater variety of chemical compounds (12 components) compared to the OD group (7 components). The highest mineral content in both groups was potassium (K), with magnesium (Mg) being higher in the OD group (15.32%) than in the FD group (9.95%). Conclusion: The drying method affects the quality and composition of Barangan banana peel. Freeze drying resulted in lower moisture content and greater phytochemical diversity, whereas oven drying tended to preserve higher mineral content for certain elements. The simplicia of Barangan banana peel from both methods has potential to be developed as a preventive dental material.

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How to Cite
Yudhit, A., Pintauli, S., Herda, E., & Dalimunthe, A. (2026). Quality of Simplicia and Composition of Barangan Banana Peel (M. acuminata Colla) as Preventive Dental Material with Different Drying Methods. Journal of Pharmaceutical and Sciences, 9(2), 1239–1245. https://doi.org/10.36490/journal-jps.com.v9i2.1391
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Original Articles

References

Lee YJ, Kim MS. Advances in drug-loaded microspheres for targeted, controlled, and sustained drug delivery: Potential, applications, and future directions. Biomed Pharmacother 2025;189:118244. https://doi.org/10.1016/j.biopha.2025.118244. DOI: https://doi.org/10.1016/j.biopha.2025.118244

Karnjana K, Jewboonchu J, Niyomtham N, Tangngamsakul P, Bunluepuech K, Goodla L, et al. The potency of herbal extracts and its green synthesized nanoparticle formulation as antibacterial agents against Streptococcus mutans associated biofilms. Biotechnol Reports 2023;37:e00777. https://doi.org/10.1016/j.btre.2022.e00777. DOI: https://doi.org/10.1016/j.btre.2022.e00777

Cheng X, Yan H, Pang S, Ya M, Qiu F, Qin P, et al. Liposomes as Multifunctional Nano-Carriers for Medicinal Natural Products. Front Chem 2022;10:1–20. https://doi.org/10.3389/fchem.2022.963004. DOI: https://doi.org/10.3389/fchem.2022.963004

Arulanandraj N, Dhivya S, Gopal V. A review on Herbal Nanoparticles. Pharmatutor 2018;6:32. https://doi.org/10.29161/pt.v6.i5.2018.32. DOI: https://doi.org/10.29161/PT.v6.i5.2018.32

Chakraborty K, Shivakumar A, Ramachandran S. Nano-technology in herbal medicines: A review. Int J Herb Med 2016;4:21–7. https://doi.org/10.22271/flora.2016.v4.i3.05. DOI: https://doi.org/10.22271/flora.2016.v4.i3.05

Nurhaslina CR, Andi Bacho S, Mustapa AN. Review on drying methods for herbal plants. Mater Today Proc 2022;63:S122–39. https://doi.org/10.1016/j.matpr.2022.02.052. DOI: https://doi.org/10.1016/j.matpr.2022.02.052

World Health Organization. Quality control methods for medicinal plant materials World Health Organization Geneva. Who 1998.

Direktorat Jenderal Kefarmasian dan Alat Kesehatan. Farmakope Herbal Indonesia. II. Jakarta: Kementerian Kesehatan RI; 2017.

Belwal T, Cravotto C, Prieto MA, Venskutonis PR, Daglia M, Devkota HP, et al. Effects of different drying techniques on the quality and bioactive compounds of plant-based products: a critical review on current trends. Dry Technol 2022;40:1539–61. https://doi.org/10.1080/07373937.2022.2068028. DOI: https://doi.org/10.1080/07373937.2022.2068028

Nakra S, Tripathy S, Srivastav PP. Drying as a preservation strategy for medicinal plants: Physicochemical and functional outcomes for food and human health. Phytomedicine Plus 2025;5:100762. https://doi.org/10.1016/j.phyplu.2025.100762. DOI: https://doi.org/10.1016/j.phyplu.2025.100762

Manalu LP, Adinegoro H, Yustiningsih N, Astuti, Luthfiyanti R, Maisaroh, et al. Impact of Drying Methods on Bioactive Compounds and Antioxidant Properties of Kalanchoe ceratophylla. Scientifica (Cairo) 2025;2025. https://doi.org/10.1155/sci5/7146758. DOI: https://doi.org/10.1155/sci5/7146758

Oliveira-Alves SC, Andrade F, Prazeres I, Silva AB, Capelo J, Duarte B, et al. Impact of drying processes on the nutritional composition, volatile profile, phytochemical content and bioactivity of salicornia ramosissima j. Woods. Antioxidants 2021;10:1–33. https://doi.org/10.3390/antiox10081312. DOI: https://doi.org/10.3390/antiox10081312

Z UBA, M H. A review of the applications of different drying methods of banana flour preparation. Food Res 2023;7:297–304. https://doi.org/https://doi.org/10.26656/fr.2017.7(1).651. DOI: https://doi.org/10.26656/fr.2017.7(1).651

Mphahlele RR, Fawole OA, Makunga NP, Opara UL. Effect of drying on the bioactive compounds, antioxidant, antibacterial and antityrosinase activities of pomegranate peel. BMC Complement Altern Med 2016;16:1–12. https://doi.org/10.1186/s12906-016-1132-y. DOI: https://doi.org/10.1186/s12906-016-1132-y

Mohd Zaini H, Roslan J, Saallah S, Munsu E, Sulaiman NS, Pindi W. Banana peels as a bioactive ingredient and its potential application in the food industry. J Funct Foods 2022;92:105054. https://doi.org/10.1016/j.jff.2022.105054. DOI: https://doi.org/10.1016/j.jff.2022.105054

Evbuomwan L, Bright Jacob I, Onodje GO, Patrick CE. Evaluating The Antibacterial Activity OF Musa acuminata (Banana) Fruit Peels Against Multidrug Resistant Bacterial Isolates. Int J Nov Res Life Sci 2018;5:26–31.

Anjum S, Sundaram S. Comparative Analysis of Antibacterial Activity of Banana Peel at Different Stages of Ripening. Int J Pharm Sci Drug Res 2023;15:1–11. https://doi.org/10.25004/ijpsdr.2023.150101. DOI: https://doi.org/10.25004/IJPSDR.2023.150101

Likittrakulwong W, Chanburee S, Kitpot T, Ninjiaranai P, Pongpamorn P. Phytochemical Properties, In Vitro Antimicrobial, and Bioactive Compounds of Banana Peel Extractions Using GC-MS. Nat Life Sci Commun 2023;22. https://doi.org/10.12982/NLSC.2023.021. DOI: https://doi.org/10.12982/NLSC.2023.021

Oyeyinka BO, Afolayan AJ. Comparative evaluation of the nutritive, mineral, and antinutritive composition of musa sinensis l. (banana) and musa paradisiaca l. (plantain) fruit compartments. Plants 2019;8. https://doi.org/10.3390/plants8120598. DOI: https://doi.org/10.3390/plants8120598

Sipahutar A, Pintauli S, Dalimunthe A. Efek Pasta Nanopartikel Kulit Pisang Barangan (Musa Paradisiaca Colla) Terhadap Permukaan Enamel Gigi Menggunakan Scanning Electron Microscopy 2024;16:85–92. DOI: https://doi.org/10.24815/cdj.v16i2.40140

Bashir S, Hussain SZ, Jan N, Naseer B, Zargar IA, Murtaza I, et al. Structural integrity, bioactive components, and physico-chemical characteristics of Kashmiri saffron (Crocus sativus L.) as affected by different drying techniques. Food Chem 2025;476. https://doi.org/10.1016/j.foodchem.2025.143511. DOI: https://doi.org/10.1016/j.foodchem.2025.143511

Nowak D, Jakubczyk E. The freeze-drying of foods⇔the characteristic of the process course and the effect of its parameters on the physical properties of food materials. Foods 2020;9. https://doi.org/10.3390/foods9101488. DOI: https://doi.org/10.3390/foods9101488

Bryan E, Ferrer-González E, Sagong HY, Fujita J, Mark L, Kaul M, et al. Structural and Antibacterial Characterization of a New Benzamide FtsZ Inhibitor with Superior Bactericidal Activity and In Vivo Efficacy Against Multidrug-Resistant Staphylococcus aureus. ACS Chem Biol 2023;18:629–42. https://doi.org/10.1021/acschembio.2c00934. DOI: https://doi.org/10.1021/acschembio.2c00934

Wrońska N, Szlaur M, Zawadzka K, Lisowska K. The Synergistic Effect of Triterpenoids and Flavonoids— New Approaches for Treating Bacterial Infections? Molecules 2022;27. https://doi.org/10.3390/molecules27030847. DOI: https://doi.org/10.3390/molecules27030847

Tzimas K, Antoniadou M, Varzakas T, Voidarou C. Plant-Derived Compounds: A Promising Tool for Dental Caries Prevention. Curr Issues Mol Biol 2024;46:5257–90. https://doi.org/10.3390/cimb46060315. DOI: https://doi.org/10.3390/cimb46060315