Review Artikel: Karakterisasi Dan Uji Efektivitas Antikanker Nanopartikel Emas (AuNPs) Dan Nanopartikel Perak (AgNPs) Dengan Ekstrak Kunyit (Curcuma spp.) Sebagai Bioreduktor
Statistik artikel
Data OJS dan sumber sitasiTayangan dan unduhan adalah aktivitas yang tercatat di OJS; pemrosesan statistik dapat tertunda. Tanda — berarti angka dari sumber tersebut belum tersedia. Cari di Google Scholar
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Izmi Haura, Munir Alinu Mulki (2025). Review Artikel: Karakterisasi Dan Uji Efektivitas Antikanker Nanopartikel Emas (AuNPs) Dan Nanopartikel Perak (AgNPs) Dengan Ekstrak Kunyit (Curcuma spp.) Sebagai Bioreduktor. Journal of Pharmaceutical and Sciences, JPS Volume 8 Nomor 4 (2025). https://doi.org/10.36490/journal-jps.com.v8i4.678
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Kanker merupakan salah satu penyebab kematian terbanyak di dunia dengan tantangan utama berupa efek samping terapi, selektivitas yang buruk, dan resistensi obat. Nanoteknologi, khususnya penggunaan nanopartikel emas (AuNPs) dan perak (AgNPs), menawarkan alternatif yang menjanjikan untuk meningkatkan efektivitas terapi kanker. Artikel ini mereview perkembangan terkini dalam sintesis AuNPs dan AgNPs menggunakan kunyit sebagai bioreduktor alami yang ramah lingkungan. Karakterisasi nanopartikel melalui metode UV-Vis, TEM, SEM, dan FT-IR menunjukkan ukuran partikel yang berkisar antara 1-100 nm, morfologi bulat atau heksagonal, serta keberadaan gugus fungsi seperti -OH dan C=O yang mendukung kestabilan dan bioaktivitas. Studi antikanker menunjukkan bahwa nanopartikel ini efektif terhadap berbagai jenis sel kanker, termasuk kanker payudara (MCF-7, MDA-MB-231), paru-paru (A549, NCI-H661, NCI-H1975, NCI-H1573, NCI-H1563), serviks (HeLa), dan epitel (Hep-2).
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Referensi
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