Drug Related Problems (DRPs) pada Pasien Mata Rawat Inap: Kajian Potong Lintang Retrospektif selama Dua Tahun
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Esthi Utaminingsih, Sholikhah Rosvita Oktasari, Zakky Cholisoh (2025). Drug Related Problems (DRPs) pada Pasien Mata Rawat Inap: Kajian Potong Lintang Retrospektif selama Dua Tahun. Journal of Pharmaceutical and Sciences, JPS Volume 8 Nomor 4 (2025). https://doi.org/10.36490/journal-jps.com.v8i4.1123
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Masalah terkait obat (drug related problems/DRPs) pada pasien mata rawat inap dapat memengaruhi efektivitas dan keamanan terapi. Penelitian ini bertujuan untuk mengidentifikasi karakteristik DRPs pada pasien mata rawat inap di RSU X Tangerang periode September 2022–Agustus 2024. Desain penelitian ini adalah retrospektif dengan pendekatan cross-sectional terhadap 178 pasien yang memenuhi kriteria inklusi. Identifikasi DRP dilakukan menggunakan klasifikasi Pharmaceutical Care Network Europe (PCNE) versi 9.1 melalui telaah resep, data klinis, dan catatan pengobatan. Analisis dilakukan secara deskriptif digunakan untuk menentukan kejadian DRP. Hasil menunjukkan bahwa sebagian besar pasien berusia 18–60 tahun (71,9%), perempuan (55,1%), tanpa komorbid (82,0%), dan menerima rata-rata lima obat selama perawatan. Terdapat empat kasus DRP (2,2%) yang terdiri atas satu kasus efektivitas terapi (P1.2) 25% dan tiga kasus keamanan obat (P2.1) 75%. Penyebab utama meliputi penggunaan obat dengan kontraindikasi meskipun sesuai pedoman (C1.2) 50%, kombinasi obat tidak tepat (C1.4) 25%, dan ketidakpatuhan pasien (C7.1) 25%. Rendahnya angka DRP kemungkinan disebabkan oleh durasi rawat inap singkat serta dominasi terapi topikal yang memiliki risiko efek sistemik rendah. Hasil ini menegaskan pentingnya peran apoteker klinis dalam pemantauan terapi untuk mencegah DRP pada pasien mata rawat inap.
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