Formulation and physical quality test of effervescent granules from turmeric extract (Curcuma longa) and tamarind (Tamarindus indica)
Article Sidebar
Main Article Content
Page: 22-31
Abstract
Empirically, turmeric tamarind is used to relieve pain and inflammation and ease menstrual cramps. However, conventional herbal preparations are currently less popular, especially among teenagers. Effervescent turmeric tamarind formulations are an innovative, practical pharmaceutical preparation with the advantage of a pleasant taste, which helps disguise the bitter flavor of turmeric. This product also provides a refreshing effect due to the acid-base reaction that produces carbon dioxide (CO2). This study aims to evaluate the physical test of effervescent turmeric tamarind granules. This experimental study formulates three turmeric-tamarind effervescent granule formulas by varying the turmeric extract dosage (Curcuma longa) to 250 mg, 500 mg, and 750 mg. The evaluations performed include organoleptic tests, water content, flow properties and angle of repose, dissolving time, and pH testing. The results showed that turmeric extract (Curcuma longa) and tamarind (Tamarindus indica) can be formulated into effervescent granules—the three formulas with different variations of turmeric extract produced good physical quality test results. Variations in the concentration of turmeric extract did not affect the physical quality of the granules.
Downloads
Article Details
This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.
References
Octavia DR, Nurafifah D, Utami PR. Formulasi dan Uji Hedonik Serbuk Effervescent Ekstrak Kunyit dengan Variasi Asam Sitrat dan Asam Tartat Article history : Public Health Faculty Received in revised form 23 September 2021 Universitas Muslim Indonesia Accepted 10 Oktober 2021 Address : Avai. Wind Heal J Kesehat 2021;4:348–57. DOI: https://doi.org/10.33096/woh.v4i04.205
Rathore S, Mukim M, Sharma P, Devi S, Chandra Nagar J, Khalid M. Curcumin: A Review for Health Benefits. Int J Res Rev 2020;7:1.
Krisnamurti GC, Bare Y, Amin M, Primiani CN. Combination of curcumin from curcuma longa and procyanidin from tamarindus indica in inhibiting cyclooxygenases for primary dysmenorrhea therapy: In silico study. Biointerface Res Appl Chem 2021;11:7460–7. https://doi.org/10.33263/BRIAC111.74607467. DOI: https://doi.org/10.33263/BRIAC111.74607467
Andriati, Wahjudi RM. Society’s Acceptance Level of Herb as Alternative to Modern Medicine for Lower, Middle, and Upper Class Group. Masyarakat, Kebud Dan Polit 2016;29:133. DOI: https://doi.org/10.20473/mkp.V29I32016.133-145
Kundarto W, Ermawati DE, Farida Y, Setyani IK, Septiana V, Rochmawati N. Peningkatan Kualitas Bentuk Sediaan Produk Minuman Jamu Kunyit Asam Melalui Pembuatan Permen Jelly di Industri Rumah Tangga Jamu Jeng In Desa Wedomartani Ngemplak Sleman Yogyakarta. J PEPADU 2020;1:106–11. https://doi.org/10.29303/jurnalpepadu.v1i1.82. DOI: https://doi.org/10.29303/jurnalpepadu.v1i1.82
Mahdiyyah M, Puspitasari IM, Putriana NA, Syamsunarno MRA. Review: Formulasi dan Evaluasi Sediaan Oral Effervescent. Maj Farmasetika 2020;5:191–203. https://doi.org/10.24198/mfarmasetika.v5i4.27278. DOI: https://doi.org/10.24198/mfarmasetika.v5i4.27278
Ismanto H. ¬Uji Organoleptik Keripik Udang (L. vannamei) Hasil Penggorengan Vakum. J AgroSainTa Widyaiswara Mandiri Membangun Bangsa 2023;6:53–8. https://doi.org/10.51589/ags.v6i2.3137. DOI: https://doi.org/10.51589/ags.v6i2.116
Elisabeth V. Formulasi sediaan granul dengan bahan pengikat pati kulit pisang goroho (Musa acuminafe L.) dan pengaruhnya pada sifar fisik granul. Pharmacon 2018;7.
Forestryana, D., Hestyarini, Y., Putri A. Formulasi Granul Effervescent Ekstrak Etanol 90% Buah Labu Air (Lagenaria siceraria) Dengan Variasi Gas Generatig Agent 2020;5:298–308. DOI: https://doi.org/10.36387/jiis.v5i2.457
Syamsul ES, Supomo. Formulation of Effervescent Powder of Water Extract of Bawang Tiwai (Eleuterine palmifolia) as A Healthy Drink. Maj Obat Tradis 2015;19:113–7.
Hadisoewignyo L, Fudholi A. Sediaan Solida. Yogyakarta: Pustaka Belajar; 2016.
Syaputri FN, Saila SZ, Tugon TDA, R. AP, Lestari D. Formulasi dan Uji Karakteristik Fisik Sediaan Granul Effervescent Ekstrak Etanol Daun Sirih Merah (Piper crocatum ruiz) Sebagai Antidiabetes. J Ilmu Kefarmasian 2023;4:191–8. DOI: https://doi.org/10.36456/farmasis.v4i1.6915
Beakawi Al-Hashemi HM, Baghabra Al-Amoudi OS. A review on the angle of repose of granular materials. Powder Technol 2018;330:397–417. https://doi.org/10.1016/j.powtec.2018.02.003. DOI: https://doi.org/10.1016/j.powtec.2018.02.003
Lachman L, Lieberman H., Kanig J. Teori dan Praktek Farmasi Industri Jilid I Edisi II. Jakarta: Universitas Indonesia; 1994.
PharmaEducation. Friability Test of Tablets, Granules, Spheroids 2023. https://pharmaeducation.net/friability-test-of-tablets/.
Sudarsono APP, Nur M, Febrianto Y. Pengaruh Perbedaan Suhu Pengeringan Granul (40°C,50°C,60°C) Terhadap Sifat Fisik Tablet Paracetamol. J Farm Sains Indones 2021;4:44–51. https://doi.org/10.52216/jfsi.v4i1.72. DOI: https://doi.org/10.52216/jfsi.v4i1.72
Putra DJS. Penggunaan Polivinill Pirolidon (PVP) Sebagai Bahan Pengikat Pada Formulasi Tablet Ekstrak Daun Sirih (Piper betle L.). J Farm Udayana 2019;8:14. https://doi.org/10.24843/jfu.2019.v08.i01.p03. DOI: https://doi.org/10.24843/JFU.2019.v08.i01.p03
Oktavina WR, Imtihani HN. Formulasi dan Evaluasi Suspensi Granul Effervescent Ekstrak Kitosan Cangkang Kepiting Bakau (Scylla serrata) Dengan Perbandingan Natrium Bikarbonat. J Islam Pharm 2023;8:62–7. https://doi.org/10.18860/jip.v8i2.23533. DOI: https://doi.org/10.18860/jip.v8i2.23533
Lestari T. Sifat Fisik Serbuk Effervescent Ramuan Jamu Antihipertensi. J Kebidanan Dan Kesehat Tradis 2019;4:45–50. https://doi.org/10.37341/jkkt.v4i1.101. DOI: https://doi.org/10.37341/jkkt.v4i1.101
Trimedona N, Rahzarni R, Muchrida Y. Karakteristik Serbuk Effervescent Dari Ekstrak Kulit Buah Naga Merah (Hylocereus polyrhizus). Lumbung 2021;20:44–54. https://doi.org/10.32530/lumbung.v20i1.335. DOI: https://doi.org/10.32530/lumbung.v20i1.335