Optimization of formulation and physical test of toner preparation from lavender essential oil (Lavandula angustifolia l.) as anti-acne
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Abstract
Lavender is a light lavender-colored flower, has a distinctive and delicate smell, and has anti-inflammatory, antiseptic, antibacterial, antifungal, antidepressant, and can reduce acne. The purpose of this study is to make a toner preparation formulation from lavender essential oil as an anti-acne with variations in glycerin and propylene glycol concentrations so that an optimal formula is produced. The method used in this study is Simplex Lattice Design. The physical tests of toner preparations carried out include organoleptic, homogeneity, pH, dry time, and displaced volume. The response from the physical evaluation was processed to obtain the optimal formula. The results of the physical test of the optimum preparation were then analyzed using the One Sample T-Test with the SPSS application. Formula optimization yielded a concentration of 10% glycerin and 7% propylenglycol. The optimal preparation of lavender toner is clear white with a distinctive lavender smell and liquid form, a homogeneous preparation, a pH value of 6.17, a drying time of 1.12 minutes, and a transferred volume of 98 ml so that the optimal preparation of lavender toner meets the requirements of a good toner. The results of the One Sample T-Test analysis showed no difference.
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References
Ginting Z, Ishak I, Ilyas M. Analisa Kandungan Patchouli Alcohol Dalam Formulasi Sediaan Minyak Nilam Aceh Utara (Pogostemon Cablin Benth) Sebagai Zat Pengikat Pada Parfum (Eau De Toilette). J Teknol Kim Unimal 2021;8:12. https://doi.org/10.29103/jtku.v10i1.4162.
Nuriska H, Mulyanti D, Ratih Aryani. Karakterisasi Minyak Lavender (Lavandula angustifolia) Untuk Alternatif Bahan Aktif Sediaan Farmasi. Bandung Conf Ser Pharm 2023:483–6. https://doi.org/10.29313/bcsp.v3i2.8914.
Ramadhan MR, Zettira OZ. Aromaterapi Bunga Lavender ( Lavandula angustifolia ) dalam Menurunkan Risiko Insomnia. Fak Kedokt Univ Lampung 2017;6:60–3.
Saragih DF, Opod H, Pali C. Hubungan tingkat kepercayaan diri dan jerawat (Acne vulgaris) pada siswa-siswi kelas XII di SMA Negeri 1 Manado. J e-Biomedik 2016;4:0–7. https://doi.org/10.35790/ebm.4.1.2016.12137.
Anggarini D, Raharjeng SW, Safitri CINH, Pangestuti Z. Formulasi dan evaluasi serum anti jerawat berbasis minyak atsiri Curcuma zedoaria. Artik Pemakalah Paralel 2021;6:406–15.
Pelen S, Wullur A, Citraningtyas G. Formulasi Sediaan Gel Antijerawat Minyak Atsiri Kulit Batang Kayu Manis (Cinnamomum Burmanii) Dan Uji Aktivitas Terhadap Bakteri Staphylococcus Aureus. Pharmacon UNSRAT 2016;5:159245.
Noor M, Malahayati S, Nastiti K. Formulasi Dan Uji Stabilitas Sediaan Toner Wajah Ekstrak Buah Pare (Momordica charantia L) Sebagai Anti Jerawat Dengan Variasi Surfaktan. J Ris Kefarmasian Indones 2023;5:133–45. https://doi.org/10.33759/jrki.v5i1.330.
Nadeak BY, Made Birawan I. the Selection of Moisturizer for Treatment of Atopic Dermatitis. Med J J Berk Ilm Kedokt 2022;5:30–9.
Subadra OS, Atikah N, Jannah FM, Khoirunisa. Formulasi Dan Uji Penangkap Radikal Bebas Metode Dpph Sediaan Toner Ekstrak Etanol Daun Belimbing Wuluh ( Averrhoa bilimbi Linn) 2023;3.
Hayati R, Sari A, Chairunnisa C. Formulasi Spray Gel Ekstrak Etil Asetat Bunga Melati (Jasminum sambac (L.) Ait.) Sebagai Antijerawat. Indones J Pharm Nat Prod 2019;2:59–64. https://doi.org/10.35473/ijpnp.v2i2.256.
Depkes RI. Farmakope Indonesia edisi IV. 2020.
Nurjanah L, Oktavilantika DM. Formulasi Toner Wajah Ekstrak Daun Pandan Wangi (Pandanus amaryllifolius Roxb.) dan Uji Aktivitas Antibakteri Terhadap Bakteri Propionibacterium acnes. J Farm Dan Farmakoinformatika 2024;2.
Liu Y, Zhang Z, Dong W. The Effect of Propylene Glycol on the Physicochemical Properties of Pharmaceutical Formulations. Journal of Pharmaceutical Formulations. J Pharm Sci 2017;106(7):2084–2090.
Karami MRAN, Malahayati S, Hidayah N, Budi S. Formulasi Dan Uji Stabilitas Sediaan Toner Anti Jerawat Ekstrak Bunga Melati (Jasminum sambac L.). J Farm SYIFA 2023;1:68–76. https://doi.org/10.63004/jfs.v1i2.235.
Nayaka NMDMW, Suradnyana IGM, Vitaloka NPGDC. Antinyamuk Dari Ekstrak Etanol Daun Legundi ( Vitex trifolia L .) 2023:37–41. https://doi.org/10.20956/mff.SpecialIssue.
Karlina DW, Noval, Yuwindry I. Formulasi dan Evaluasi Nano Spray Gel dengan Ekstrak Daun Sirih Merah ( piper crocatum Ruiz & Pav ) Sebagai Antioksidan dengan Variasi Konsentrasi Carbopol 940. J Surya Med 2024;10 (2):288–301.
Nadiya I, Haryati S, Surilayani D, Hasanah AN. Karakteristik Pemanfaatan Ekstrak Rumput Laut (Kappaphycus alvarezii) dan Teh Hijau (Camellia sinensis) sebagai Sediaan Hydrating Toner. J Perikan Dan Kelaut 2024;13:157. https://doi.org/10.33512/jpk.v13i2.22657.
Damayanti DAT. Rancangan Formulasi Dan Teknologi Sediaan Steril Injeksi Fenitoin Serta Uji Evaluatif Sediaan. J Kesehat Tambusai 2024;5:3059–67.
Widnyana IKAW, Subaidah WA, Hanifa NIH. Optimasi Formula Stick Balm Minyak Atsiri Daun Sereh (Cymbopogon citratus). J Penelit Farm Indones 2021;10:16–24. https://doi.org/10.51887/jpfi.v10i2.1417.
Ameliana L, Wisudyaningsih B, Nurahmanto D, Dianatri YAM. Pengembangan Essence dari Ekstrak Kayu Secang (Caesalpinia sappan L.). J Ilmu Kefarmasian Indones 2022;20:101. https://doi.org/10.35814/jifi.v20i1.1139.
Silvia B., Dewi M. Studi Literatur Pengaruh Jenis dan Konsentrasi Basis terhadap Karakteristik Masker Gel Peel Off. J Ris Farm 2022;2:31–40.
Ittiqo DH, Wahid AR. Optimasi Formula Gel Serbuk Getah Ashitaba (Angelica keiskei Koidzumi) dan Uji Aktivitas Terhadap Lama Penyembuhan Luka Eksisi pada Kelinci. Pharmauho J Farm Sains, Dan Kesehat 2019;4. https://doi.org/10.33772/pharmauho.v4i2.6258.