ANTIOXIDANT ACTIVITY TESTING OF MANGGOST (Garcinia mangostana L.) SKIN EXTRACT IN SERUM PREPARATION WITH DPPH METHOD
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syarifah nadia maulina, Nilsya Febrika Zebua, dafitri salsabila (2022). ANTIOXIDANT ACTIVITY TESTING OF MANGGOST (Garcinia mangostana L.) SKIN EXTRACT IN SERUM PREPARATION WITH DPPH METHOD. Journal of Pharmaceutical and Sciences, Vol. 5 No. 2 (2022): JPS Volume 5 Nomor 2 (2022). https://doi.org/10.36490/journal-jps.com.v5i2.129
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Abstract
Mangosteen rind has antioxidant compounds that can counteract free radicals. Serum is a liquid enriched with active ingredients such as antioxidants that are able to penetrate into the facial skin. This research used experimental method, using mangosteen rind test material (Garcinia mangostana L.) which was obtained by extraction method using ethanol pa. The stages of this research include the manufacture of extracts from mangosteen rind and formulated into serum preparations in several concentrations, namely 3%, 4%, 5%, blank and continued with physical quality examination of the preparation. The results of the homogeneity test showed that all serum preparations were homogeneous. The pH test results showed a pH of 6.0-6.4. Viscosity test results show 1268-1870 mPa's. The results of the stability test showed that all preparations were stable. The results of the irritation test showed that all preparations were not irritating. The results of the preference test showed that the F2 preparation with a concentration of 4% was the most preferred. The preparation with the best concentration was 5% (F3) with an IC50 value of 31.92 ppm. This proves that the antioxidant activity of the mangosteen rind extract serum is very strong.
Keywoard : Mangosteen Peel, Serum, Antioxidants
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