POTENTIAL ANTI-BACTERIAL POWDER BOOTING WATER, n-HEXANA EXTRACT AND EARTHWORM CHLOROFORM EXTRACT (Peryonix sp.) AGAINST Salmonella typhosa BACTERIA
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Keywords

Salmonella typhosa
in vitro
traditional Chinese medicines
Anti-bacterial activity
Earthworm (Perionyx sp.)

How to Cite

Indriana, M., & salman, salman. (2020). POTENTIAL ANTI-BACTERIAL POWDER BOOTING WATER, n-HEXANA EXTRACT AND EARTHWORM CHLOROFORM EXTRACT (Peryonix sp.) AGAINST Salmonella typhosa BACTERIA. Journal of Pharmaceutical And Sciences, 3(1), 62-68. https://doi.org/10.36490/journal-jps.com.v3i1.89
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Abstract

Earthworms are animals that have many benefits and are easy to find—results of information from people consume boiled water of earthworms three times a day for 7 days is used as a typhus medicine, other information is obtained from electronic media, many people also consume earthworms as a typhoid medicine in powder form which is filled into capsules Which can be found in Chinese drug stores, but until now scientific research on earthworms (Perionyx sp.) as an anti-bacterial has not been done. Extraction is done by maceration. Multilevel maceration using chloroform and n-hexane as solvent. The class of chemical compounds was determined on the ethyl acetate extract and the n-hexane extract of the earthworm Perionyx sp.), including alkaloids, glycosides, steroids/triterpenoids, flavonoids, saponins, and tannins. Testing of antibacterial activity of chloroform extract and n-hexane extract against Salmonella typhosa was carried out in vitro by agar diffusion method using metal buffer at a concentration of 500 mg/ml; 400 mg/ml; 300 mg/ml; 200 mg/ml; 100 mg/ml and 50 mg/ml. The results of determining the class of chemical compounds from the chloroform extract of earthworms (Perionyx sp.) showed the presence of chemical compounds belonging to the alkaloid group, while the n-hexane extract did not indicate the presence of chemical compounds detected. The n-hexane extract of tar h (Perionyx sp.) had an inhibitory effect on the growth of Salmonella typhosa at a minimum inhibitory concentration of 400 mg/ml of 10.9mm, while the chloroform extract had a minimum inhibitory concentration of 300 mg/ml with an inhibitory diameter of 12.87 mm.

https://doi.org/10.36490/journal-jps.com.v3i1.89
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