Pemetaan Saintifik terhadap Potensi Tanaman Brassicaceae sebagai Anti-inflamasi: Analisis Bibliometrik Periode Tahun 2003−2024
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Brassicaceae adalah famili tanaman yang dikenal dengan aktivitas antioksidan dan anti-inflamasinya. Distribusi yang luas membuat tanaman ini berperan sebagai sumber fitokimia bioaktif yang penting, sehingga menarik minat penelitian yang signifikan. Tanaman Brassicaceae mengandung beberapa metabolit sekunder, termasuk glukosinolat, yang merupakan prekursor senyawa bioaktif seperti isotiosianat (misalnya sulforafan) yang telah terbukti memiliki efek anti-inflamasi. Penelitian ini bertujuan untuk menyelidiki kata kunci, negara, jumlah publikasi, institusi, penulis, dan jurnal penerbit yang terkait dengan tanaman Brassicaceae sebagai anti-inflamasi pada periode tahun 2003−2024 menggunakan metode analisis bibliometrik yang komprehensif. Informasi dikumpulkan menggunakan basis data Scopus, diikuti dengan analisis data menggunakan Biblioshiny R Package dan VOSviewer. Total publikasi sebanyak 760 artikel yang memenuhi kriteria inklusi kemudian dianalisis. Hasil analisis menunjukkan bahwa tahun 2023 mengalami peningkatan terbesar dalam publikasi penelitian, dengan negara China muncul sebagai kontributor utama, sementara USA memiliki jumlah sitasi tertinggi. International Journal of Molecular Sciences diidentifikasi sebagai jurnal penerbit yang terpopuler. Kyung Hee University ditetapkan sebagai institusi terproduktif, dengan Li Y sebagai penulis yang memberikan kontribusi tertinggi. Data bibliometrik juga menggambarkan beberapa molekul target terapeutik termasuk sitokin, oksida nitrit, siklooksigenase-2, dan Nrf2 yang berperan penting terhadap mekanisme aksi senyawa metabolit khas tanaman Brassicaceae seperti sulforafan, isotiosianat, glukosinolat, dan flavonoid untuk tujuan terapeutik sebagai anti-inflamasi, antioksidan, antimikrobial, dan kemopreventif. Temuan ini menekankan potensi signifikan pengembangan tanaman obat Brassicaceae untuk berbagai mekanisme terapeutik dan memberikan rekomendasi untuk penelitian di masa depan dalam bidang farmasi.
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