Korelasi ETDQ-7 dengan Pemeriksaan Fungsi Tuba Eustachius dan Timpanometri pada Pasien Karsinoma Nasofaring Pasca Kemoradioterapi

Abstrak

Eustachian tube dysfunction commonly occurs in patients with nasopharyngeal carcinoma (NPC), particularly following chemoradiotherapy. Tubal dysfunction after chemoradiotherapy results from a combination of obstruction and functional impairment, making evaluation of Eustachian tube function essential. The Eustachian Tube Dysfunction Questionnaire-7 (ETDQ-7) is a validated, brief questionnaire used to identify patients at risk of Eustachian tube dysfunction. This study aimed to assess the association between ETDQ-7 scores and the results of Eustachian Tube Function Testing (ETF) and tympanometry in nasopharyngeal carcinoma patients following chemoradiotherapy. This study used a cross-sectional analytic design conducted at the ENT-Head and Neck Surgery outpatient clinic from February to May 2026. Eustachian tube dysfunction was assessed using ETDQ-7 with a cut-off of ≥3, and results were compared with ETF and tympanometry findings. The association between variables was analyzed using the Fisher-Exact test. A total of 66 patients were included, with a mean age of 58.08±8.71 years, and the majority were male (75.8%). Based on ETDQ-7, 56.1% of patients had moderate-grade tubal dysfunction and 15.2% had severe-grade dysfunction. A significant association was found between ETF and ETDQ-7 (p<0,001; CC 0,583; Cramér's V 0,717; CI 95% 0,546–0,803) and between tympanometry and ETDQ-7 (p<0,001; CC 0,620; Cramér's V 791; CI 95% 0,673–0,864), with a stronger association observed for tympanometry compared to ETF. Eustachian tube dysfunction remains commonly found in NPC patients following chemoradiotherapy. ETDQ-7 scores show a significant association with ETF and tympanometry findings, suggesting its potential use as a simple and easily applicable initial screening method for detecting Eustachian tube dysfunction in NPC patients after chemoradiotherapy.