Main Article Content

Diah Kartika Putri
Salsabila Jelita
Vicko Suswidiantoro
Hardono

Page: 2175-2183

Abstract

Patients with Chronic Kidney Disease (CKD) undergoing hemodialysis experience various physical, psychological, and social disturbances that negatively impact their quality of life. While hemodialysis sustains life, this study aimed to identify respondent characteristics and analyze the influence of age, gender, education, occupation, hemodialysis frequency, and duration of hemodialysis on the quality of life of CKD patients undergoing the procedure, as well as to determine the most dominant factor influencing their quality of life. A non-experimental research design with a cross-sectional approach was employed. The study involved 65 respondents selected via purposive sampling and was conducted at the Hemodialysis Unit in February 2026. Data were collected using the KDQOL-SF 36 questionnaire and analyzed using Pearson Correlation, Independent T-test, One-Way ANOVA, and Multiple Linear Regression. Bivariate analysis results indicated that age (p=0,004), occupation (p=0,005), and duration of hemodialysis (p=0,014) were significantly associated with the quality of life of CKD patients, whereas gender (p=0,656) and education level (p=0,117) showed no significant association. Multivariate analysis revealed that the duration of hemodialysis was the most dominant factor influencing patients' quality of life (β=6,781; p=0,028), with the model explaining 25% of the variation in quality of life (R²=0,25). Thus, the duration of hemodialysis is the dominant factor affecting the quality of life of CKD patients; the longer patients undergo hemodialysis therapy, the better their ability to adapt to the disease and treatment, leading to a tendency for improved quality of life.

Downloads

Download data is not yet available.

Article Details

How to Cite
Putri, D. K., Jelita , S., Suswidiantoro , V., & Hardono, H. (2026). Dominant Factors Influencing the Quality of Life of Chronic Kidney Failure Patients Undergoing Hemodialysis. Journal of Pharmaceutical and Sciences, 9(3), 2175–2183. https://doi.org/10.36490/journal-jps.com.v9i3.1754
Section
Original Articles

References

V. Natalia, Z. R. Kasim, and D. M. Silvia, “Hubungan Lama Menjalani Terapi Hemodialisa Dengan Kualitas Hidup Pasien Chronic Kidney Disease (CKD) di Ruang Hemodialisa Melati RSUP Prof. Dr. R. D. Kandou Manado,” J. Kesehat. Amanah, vol. 4, no. 2, pp. 70–93, 2020, doi: 10.57214/jka.v4i2.191.

WHO, “Guidelines for the Management of Typhoid Fever.,” World Heal. Organ., no. July, 2011.

ISN, “KDIGO 2024 Clinical Practice Guideline For The Evaluation And Management Of Chronic Kidney Disease,” Kidney Int., vol. 59, no. 5, pp. 1995–2001, 2024, doi: 10.1046/j.1523-1755.2001.0590051995.x.

Kemenkes, “Keputusan Mentri Kesehatan Republik Indonesia Nomor HK.01.07 Tahun 2023 Tentang Pedoman Nasional Pelayanan Kedokteran Tata Laksana Penyskit Ginjal Kronik,” Kementrian Kesehat. Republik Indones., no. 11, pp. 1–189, 2023, [Online]. Available: https://www.kemkes.go.id/id/pnpk-2023---tata-laksana-penyakit-ginjal-kronik

P. S. Sari, R. AZ, and M. Maulani, “Hubungan Lama Hemodialisis dengan Kualitas Hidup Pasien Penyakit Ginjal Kronik di Ruang Hemodialisa Rumah Sakit Bhayangkara Kota Jambi,” J. Ilm. Ners Indones., vol. 3, no. 2, pp. 54–62, 2022, doi: 10.22437/jini.v3i2.20204.

N. Z. Aditama, H. Kusumajaya, and N. Fitri, “Faktor Faktor Yang Berhubungan Dengan Kualitas Hidup Pasien Gagal Ginjal Kronis,” J. Penelit. Perawat Prof., vol. 6, no. 1, pp. 109–120, 2024.

R. Simorangkir, T. M. Andayani, and C. Wiedyaningsih, “Faktor-Faktor yang Berhubungan dengan Kualitas Hidup Pasien Penyakit Ginjal Kronis yang Menjalani Hemodialisis,” J. Farm. Dan Ilmu Kefarmasian Indones., vol. 8, no. 1, pp. 83–90, 2021.

L. Rafliyani, R. Suparman, M. Mmlukah, and E. Febriani, “Analisis faktor yang berhubungan dengan kualitas hidup pasien gagal ginjal kronik yang menjalani hemodialisis,” J. Public Heal. Innov., vol. 5, no. 1, pp. 110–119, 2024, doi: 10.34305/jphi.v5i01.1424.

L. Aini, L. Astuti, and S. Maharani, “Faktor Faktor Yang Berhubungan Dengan Kualitas Hidup Gagal Ginjal Kronik (GGK) Yang Menjalani Hemodialisa,” J. Ilmu Kedokt. Dan Kesehat., vol. 8, no. 2, pp. 111–119, 2021.

R. Tampake and A. D. S. Doho, “Characteristics of Chronic Kidney Disease Patients Who Undergo Hemodialysis,” Lentora Nurs. J., vol. 1, no. 2, pp. 39–43, 2021, doi: 10.33860/lnj.v1i2.500.

P. A. L. Berek, Y. L. U. F. Dales, and M. F. W. A. Fouk, “Hubungan Antara Umur dan Jenis Kelamin dengan Kualitas Hidup Pasien Gagal Ginjal Kronik yang Menjalani Hemodialisis,” J. Ris. Rumpun Ilmu Kedokt., vol. 04, no. 01, pp. 230–242, 2025.

H. Golang, I. Muhafilah, and Q. A. Wulan, “Hubungan Antara Karakteristik Individu dengan Kualitas Hidup Pasien Gagal Ginjal di Ruang Hemodialisa RS Bhayangkara Tk I Raden Said Sukanto,” J. Kesehat. Masy. Perkota., vol. 4, no. 1, pp. 1–12, 2024.

S. Rahmah, Maryunis, and Ernasari, “Faktor yang Berhubungan dengan Kualitas Hidup Pasien Penyakit Ginjal Kronik yang Menjalani Hemodialisis Article history :,” Wind. Nurs. J., vol. 02, no. 02, pp. 165–177, 2021.

R. P. Priandini, L. Handayani, and Rosyidah, “Faktor - Faktor yang Berhubungan dengan Kualitas Hidup ( Quality Of Life ) Pasien Gagal Ginjal Kronik yang Menjalani Hemodialisa,” J. Pendidik. Tambusai, vol. 7, no. 1, pp. 3332–3338, 2023.

K. D. Anggita and V. Oktia, “Gambaran Kualitas Hidup Pasien Gagal Ginjal Kronis (GGK) Yang Menjalani Hemodialisis,” J. Ilmu Kesehat., vol. 2, no. 8, pp. 277–284, 2023.

A. M. Gretchen and R. J. Mandias, “Lama Menjalani Hemodialisa Dengan Kualitas Hidup Pasien Yang Menjalani Hemodialisa,” Klabat J. Nurs., vol. 7, no. 2, pp. 291–298, 2025.

K. Andu, Alfianur, N. Hidaya, M. I. Ose, and R. A. Tukan, “Hubungan lama menjalni hemodialisis dengan kualitas hidup pasien gagal ginjal kronik di RSUD Dr. H Jusuf SK,” J Kep Cikini, vol. 5, no. 2, pp. 240–251, 2024, http://dx.doi.org/10.1038/s41587-020-05

S. Natalia, F. Suangga, W. Pramadhani, and Isnaini, “Hubungan Antara Lama Menjalani Hemodialisa Dengan Kualitas Hidup Pasien Gagal Ginjal Kronik Di Ruang Hemodialisa Di Salah Satu RSUD Di Batam,” An-Najat, vol. 1, no. 2, pp. 108–115, 2023, doi: 10.59841/an-najat.v1i2.162.

F. G. Ranggini, A. Krisnasary, and Kamsiah, “Jurnal Gizi dan Dietetik Indonesia Length of hemodialysis , fluid intake , and quality of life in patients with chronic kidney disease,” Indones. J. Nutr. Diet., vol. 12, no. 6, pp. 457–463, 2024.

A. R. Bello et al., “Better health-related quality of life is associated with prolonged survival and reduced hospitalization risk among dialysis-dependent chronic kidney disease patients : a historical cohort study,” BMC Nephrol., vol. 4, no. 6, pp. 67–74, 2024.

T. Tasnim, K. Muhammad, R. Karim, T. Rahman, and H. Rashid, “Health-related quality of life and its predictors among chronic kidney disease patients : A hospital-based cross-sectional study,” PLoS One, vol. 6, no. 5, pp. 1–20, 2025, doi: 10.1371/journal.pone.0319100.