Abstract
Local cardamom (Amomumcompactum Sol. Ex Manton) is able to inhibit the growth of fungi and cineol compounds. Local cardamom which is anti-fungal and contains antibacterial properties. This study aims to determine the ethanol extract of cardamom fruit which is formulated into a mouthwash that can inhibit the growth of bacteria Staphylococcus aureusand Streptococcus mutans at certain concentrations. The method of this research is to test the antibacterial activity of Staphylococcus aureus and Streptococcus mutansfrom the ethanol extract of cardamom mouthwash. The preparation was evaluated for physical stability of storage for 4 weeks, pH test and antibacterial test. All cardamom fruit ethanol extract mouthwash preparations have a good physical form and are stable. At 4 weeks of storage, do not have the appropriate pH and antibacterial activity of cardamom fruit ethanol extract mouthwash against Staphylococcus aureus and Streptococcus mutans 2%, 4%, and 6% for Streptococcus mutans, the inhibition diameter was 9 mm, and 8 mm, while Staphylococcus aureus had the inhibition diameter 12 mm, 11 mm, and 10 mm, respectively. The results of this study concluded that the ethanol extract of cardamom fruit can be formulated into mouthwash with concentrations of 2%, 4%, and 6% which have moderate inhibition against Streptococcus mutans bacteria and have strong category inhibition against Staphylococcus aureus bacteria.
References
Amos. 2009. Gambir Sebagai Anti Bakteri dalam Formulasi Obat Kumur. Jakarta: Jurnal Sains dan Teknologi Indonesia. Halaman 188-192.
Amtha, R. 1997. Kelainan Mukosa Mulut Akibat Penggunaan Obat Kumur. Skripsi. Jakarta: Fakultas Kedokteran dan Ilmu Kesehatan. Halaman 21.
Depkes RI. 1995. Farmakope Indonesia Edisi IV. Jakarta: Gadjah Mada University Press. Halaman 174.
Hembing, W. K. 1998. Tanaman Berkhasiat Obat di Indonesia Jilid ke-4. Jakarta: Penebar Swadaya. Halaman 23-25.
Prasasty, suranto., Styaningsih. 2003. Aktivitas anticendawan biji dan buah kapulaga (Amomum cardamomum willd.) terhadap botrytis cineria pers. Asal buah anggur (vitissp.), Bio SMART. Jurnal Media Farmasi.Halaman 61-64.
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