Sexual dysfunction is a condition where sexual intercourse is difficult. Sexual dysfunction includes erectile dysfunction, impotence, premature ejaculation and disorders of desire (libido). One of the ways to overcome sexual disorders is by using aphrodisiac. Aphrodisiac is a kind of stimulating substance that can increase sex drive. One of the fruits that has an aphrodisiac effect is watermelon, precisely on the white layer on the skin that contains citrulline. This study aims to determine the aphrodisiac potential and the number of effective doses of watermelon albedo (mesocarp) ethanol extract (WAEE) against mice using ICC (Introducing, Climbing and Coitus). This research is an experimental study using 30 mice and divided into 5 groups. Group I (negative control) CMC 0.5%; group II (positive control) Pasak Bumi herbal medicine; group III; IV; V WAEE at a dose of 7; 13; and 27 g / kgBB. The mice were given orally and the ICC intensity was calculated. ICC intensity was statistically analyzed using the One Way ANOVA method and Duncan's Post-Hoc test using SPSS 24.0. The results of the ICC intensity statistical test between the Pasak Bumi herbal medicine and EEAS groups showed no significant difference with a value of α> 0.05. From the results of the study it can be concluded that EEAS has the potential as an aphrodisiac in mice with the most effective dose of 13 g / kgBW.
Andri, W. Y. 2010. Produksi Mencit Putih (Mus musculus) dengan Substitusi Bawang Putih (Allium sativum) dalam Ransum. Skripsi. Bogor: Fakultas Peternakan Institut Pertanian Bogor. Halaman 3-5.
Arisandi, Y. 2008. Difungsi Seksual. Semarang: Garda. Hal. 139.
Citraningtyas, G. 2015. Uji Efek Afrodisiaka Ekstrak Etanol Buah Pare (Momordica Carantia L.) terhadap Libido Tikus Putih Jantan Galur Wistar (Ratus norvegicus). Jurnal Pharmacon. 4(3): 147-149.
Depkes RI. 2010. Farmakope Herbal Indonesia. Jakarta: Depkes RI. Halaman 113-115.
Harmusyanto, R. 2013. Studi Mengenai Efek Daun Katuk (Sauropus Androgynus (L) Merr.)Terhadap Libido Kelinci Jantan (Oryctolagus Cuniculus) Sebagai Afrodisiak. Jurnal Fakultas Farmasi Universitas Surabaya. 2(1): 5-6.
Hidayat, A. 2012. Kebutuhan Dasar Manusia. Surabaya: Health Books Publishing. Halaman 6-7.
Indrisari, M., Rahimah, St.,Umar, A. H dan Allyah, A. P. 2013. Uji Efek Afrodisiaka dari Ekstrak Bawang Putih (Alliumsativum) pada Hewan Coba Mencit (Mus musculus). Jurnal Farmasi Akademi Farmasi Kebangsaan Sekolah Tinggi Ilmu Farmasi. 2: 140-144.
Oktavina, D.M. 2006. Ramuan Afrodisiak Nusantara Pembangkit Gairah. Jakarta: Esensi. Halaman 76.
Rochmatika, D. 2012. Analisis Kadar Antioksidan Pada Masker Wajah Berbahan Dasar Lapisan Putih Kulit Semangka (Citrullus Vulgaris Schard). Seminar Nasional Penelitian, Pendidikan dan Penerapan MIPA. Yogyakarta: Universitas Negeri Yogyakarta. Hal. 1-2.
Yulisbeth, A. 2018. Aktivitas Fraksi n-butanol Cawat Hanoman (Libicia pumila) terhadap Mencit Jantan. Karya Ilmiah. Kalsel: Universitas Lambung Mangkurat. Hal. 10.
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