Effects of Hypoglycemia on Patients with Type 2 Diabetes Mellitus on Therapy Adherence and Quality of Life
PDF (Bahasa Indonesia)

Keywords

hypoglycemia
tipe 2 diabetes mellitus
adherence
quality of life

How to Cite

Rusdi, M., & Afriyeni, H. (2019). Effects of Hypoglycemia on Patients with Type 2 Diabetes Mellitus on Therapy Adherence and Quality of Life. Journal of Pharmaceutical And Sciences, 2(1), 24-29. https://doi.org/10.36490/journal-jps.com.v2i1.13
Abstract viewed = 844 times
PDF (Bahasa Indonesia) downloaded = 692 times

Abstract

Diabetes mellitus (DM) is a metabolic disorder characterized by an increase in blood sugar due to a decreasing in insulin secretion by pancreatic beta cells and/or impaired insulin function (insulin resistance). Based on the International Diabetes Federation (IDF) (2015), Indonesia was ranked 7th in the world with 10 million people suffered from DM. DM can become serious and cause a chronic condition that is dangerous if not treated and not adhered in taking medication. The main risks associated with DM are hypoglycemia, hyperglycemia, diabetic ketoacidosis, dehydration, and thrombosis. The incidence of hypoglycemia can be influenced by age factors, duration of suffering from diabetes, weight, and glycemic control. Acute and chronic complications of hypoglycemia can interfere with life, such as social interaction, sleep, sexual activity, driving, sports, and other activities.

The purpose of this study was to determine the effect of hypoglycemia in type 2 DM patients on therapy adherence and quality of life. The design of this study was a cross-sectional study with subjects of the research were adult patients with type 2 DM who used oral anti-diabetes medication for more than 6 months. Patients who have a history of hypoglycemia are divided into 3 groups, namely (1) Having hypoglycemia in the last 3 months; (2) Not experiencing hypoglycemia in the last 3 months; (3) Never experience hypoglycemia.

Measurement of adherence using the Morisky Modified Adherence Scale (MMAS), measurement of quality of life with Diabetes Quality of Life Questionnaire (DQoL), data obtained will be processed statistically using Chi-Square Test. The result of this study was unable to prove the relationship of hypoglycemia to therapy adherence (p = 0.756; p> 0.05) and the quality of life of patients (p = 0.143; p> 0.05).

https://doi.org/10.36490/journal-jps.com.v2i1.13
PDF (Bahasa Indonesia)

References

Bays H.E., Chapman R.H., Grandy, S. 2007. the relationship of Body Mass Index to Diabetes, hypertension, and Dyslipidemia: Comparison of Data from Two National Surveys. Int J Clin Pract 61:737 - 747

Burroughs T.E., Desikan, R., Waterman B.M., Gilin D., McGill J. 2004. Development and Validation of Diabetes Quality of Life Life Brief Clinical Inventory. Diabetes Spsctrum. 17 (1): 41 - 49

Erol, O., Enc, N. 2011. Hypoglycemia Fear and Self-efficacy of Turkish Patients Receiving Insulin Therapy. Asian Nursing Research(5): 222 – 228

Fidler C., Christensen T.E., Gillard S. 2011.Hypoglicemia: An Overview of fear of Hypogliecemia, Quality of Life, and Impact on Cost. Journal of Medical Economics. 14(5):646-655

International Diabetes Federation.2015.IDF Diabetes Atlas Seventh Edition. Brussels, Belgium: International Diabetes Federation.

International Diabetes Federation and the DAR International Alliance (IDF-DAR). 2016. Diabetes And Ramadan: Practical Guidelines. Brussels, Belgium: International Diabetes Federation

Kautzky-Willer, A., Harreiter J., dan Pacin, G. 2016. Sexes and Gender Differences in risk, Pathophysiology and Complications of Type 2 Diabetes Mellitus. Endocrine Reviews 37;3: 278 - 316.

Lopez, J., Annunziata, K., Bailey, A., Rupnow, M., Morisky, D. 2014. Impact Of Hypoglycemia On Patients With Type 2Diabetes Mellitus And Their Quality Of Life, Work Productivity, And Medication Adherence. Dove Press - Patient Preference and Adherence.8:683 - 692

Mihardja, L., Soetrisno, U., Soegondo, S.2014. Prevalence and clinical profile of diabetes in productive aged urban Indonesia. Journal of Diabetes Investigation 5;507 - 512

Min H., Jong, W.C., Balkhrisna, R. 2010. Sociodemographic risk factorof diabetes and hypertension prevalence in republic of Korea. Int J Hypertens 410794

Morisky DE, Ang A, Krousel-Wood M, Ward HJ. 2008. Predictive validityof a medication adherence measure in an outpatient setting. J Clin hypertensi(Greenwich). 10:348–354.

Pramono dan Aswin L. 2010. Prevalensi dan Faktor - Faktor Prediksi Diabetes Melitus Tidak Terdiagnosa pada Penduduk Usia Dewasa di Indonesia. Tesis. Depok: FKMUI

Schofield, J.D., Lium Y., Soran H. Balakrishna P.R., Malik, R.A. 2016. Diabetes Dylipidemia. Diabetes Ther 7(2): 203 - 219

Venugopal K, Mohammed M Z. Prevalence of hypertension in type-2 diabetes mellitus. CHRISMED J Health Res 2014;1:223-7

Walz, L., Petterson, B., Rosenqvist, U., Deleskoq, A., Journath, G., Wandell, P. 2014. Impact of Symptomatic Hypoglycemia on Medication Adherence, Patient Satisfaction with Treatmenr, and Glycemic Control in Patients with Type 2 Diabetes. Patient Preference And Adherence. (8):593 – 601.


This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License

Journal Pharmaceutical And Sciences (JPS) is published under the terms of the Creative Commons Attribution-Share. According to license under a Commons Attribution Non-Commercial ShareAlike 4.0

Authors retain the copyright to their work. Users can freely read, print, copy, and distribute material/works in any form, media, or format, provided the author and Journal Pharmaceutical And Sciences (JPS) are properly credited or cited. Authors are permitted to also store the published article at other websites or database systems.

Authors are permitted to distribute the published article to colleagues, post it to open websites - non-commercial, reuse of portions or extracts from the articles in other works, and text & data mining. However, authors are not allowed to send their manuscript to other scientific journals once it has been decided to be reviewed by reviewers at Journal Pharmaceutical And Sciences (JPS).

Downloads

Download data is not yet available.