Comparison Of Antibacterial Of Sambiloto (Andrographis paniculata) Leaf and Kemangi (Ocimum sanctum) Leaf Extract against Staphylococcus aureus
Vol 5 No 2 (2022), Articles
Vol 5 No 2 (2022)

Comparison Of Antibacterial Of Sambiloto (Andrographis paniculata) Leaf and Kemangi (Ocimum sanctum) Leaf Extract against Staphylococcus aureus

Articles
https://doi.org/10.36490/journal-jps.com.v5i2.141
Published December 2, 2022
Eria Khoirunisa Amelia
Universitas Singaperbangsa Karawang
Lely Sulfiani Saula
Program Studi Farmasi, Fakultas Ilmu Kesehatan, Universitas Singaperbangsa, Karawang, Indonesia
Ahsanal Kasasiah
Program Studi Farmasi, Fakultas Ilmu Kesehatan, Universitas Singaperbangsa, Karawang, Indonesia
pdf (Bahasa Indonesia)

Keywords

Kemangi (Ocimum sanctum) Leaves
Sambiloto (Andrographis paniculata) Leaves
Escherichia coli

How to Cite

Amelia, E., Saula, L., & Kasasiah, A. (2022). Comparison Of Antibacterial Of Sambiloto (Andrographis paniculata) Leaf and Kemangi (Ocimum sanctum) Leaf Extract against Staphylococcus aureus. Journal of Pharmaceutical And Sciences, 5(2), 286-293. https://doi.org/10.36490/journal-jps.com.v5i2.141
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Abstract

Escherichia coli infection can be treated with antibiotics. However, antibiotic resistance can occur if its use is inappropriate for adopting alternative therapies, including developing therapy with the potential of medication based on plants. Sambiloto (Andrographis paniculata) and kemangi (Ocimum sanctum) leaves are two substitutes that can be utilized in medicine as antibacterial agents. This research was conducted to analyze the comparison of inhibition of kemangi (Ocimum sanctum) leaves, sambiloto (Andrographis paniculata) leaves, and a combination of both against the growth of Escherichia coli bacteria in vitro. Test for inhibition activity used a paper disc diffusion method. The results showed that the extract of kemangi (Ocimum sanctum) leaves and sambiloto (Andrographis paniculata) leaves obtained the highest inhibition zone occurring at concentrations of 100%. In the combination test of the two extracts, a concentration of 50%:50% gave the most optimum inhibition zone with an average diameter of 33,1 mm. The one-way ANOVA statistical (p=0.001) results showed a significant difference in the diameters of the inhibition zone of each treatment group on the growth of Escherichia coli bacteria.

https://doi.org/10.36490/journal-jps.com.v5i2.141
pdf (Bahasa Indonesia)

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