Antimicrobial Activity Jangjingki (Oxalis corniculata L.) Against The Growth Of Staphylococcus Aureus, Escherichia Coli, and Candida Albicans
Vol 4 No 1 (2021), Articles
Vol 4 No 1 (2021)

Antimicrobial Activity Jangjingki (Oxalis corniculata L.) Against The Growth Of Staphylococcus Aureus, Escherichia Coli, and Candida Albicans

Articles
https://doi.org/10.36490/journal-jps.com.v4i1.58
Published June 26, 2021
Misrahanum Misrahanum
Jurusan Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Syiah Kuala
Syarifah Dhea Almunawwarah
Jurusan Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Syiah Kuala
Hira Helwati
Jurusan Kimia, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Syiah Kuala
Hilda Maysarah
Jurusan Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Syiah Kuala
Sadli Sadli
Jurusan Farmasi, Fakultas Matematika dan Ilmu Pengetahuan Alam, Universitas Syiah Kuala
PDF

Keywords

Antimicrobial
angjingki
methanol extract
Staphylococcus aureus
Escherichia coli
Candida albicans.

How to Cite

Misrahanum, M., Almunawwarah, S., Helwati, H., Maysarah, H., & Sadli, S. (2021). Antimicrobial Activity Jangjingki (Oxalis corniculata L.) Against The Growth Of Staphylococcus Aureus, Escherichia Coli, and Candida Albicans. Journal of Pharmaceutical And Sciences, 4(1), 1-11. https://doi.org/10.36490/journal-jps.com.v4i1.58
ACM ACS APA ABNT Chicago Harvard IEEE MLA Turabian Vancouver

Download Citation

Endnote/Zotero/Mendeley (RIS) BibTeX
Abstract viewed = 124 times
PDF downloaded = 98 times

Abstract

Jangjingki (Oxalis corniculata L.) is a plant from Oxalidaceae that has potential as a natural antimicrobial agent. The purpose of this research is to see the antimicrobial activity of methanol extract of jangjingki against the growth of Staphylococcus aureus ATCC 25923, Escherichia coli ATCC 25922, and Candida albicans ATCC 10231. The thick extract of jangjingki was obtained by the maceration method with methanol solvent. At the same time, the antimicrobial activity test on S. aureus and E. Coli bacteria was carried out using the hole diffusion method. The simplicia characterization showed 7.17% water, 9.68% of total ash, 11.67% water-soluble extract, and 9.17% of the ethanol-soluble section. At the same time, the methanol extract of jangjingki characterization showed 22.5% of water, 10.16% of total ash, 55.83% water-soluble extract, and 62.91% of the ethanol-soluble section. Phytochemical test results showed that the methanol extract of jangjingki contains alkaloids, saponins, flavonoids, tannins, and steroids. The results of the antimicrobial activity test with variations in the concentration of jangjingki methanol extract 15, 20, 30, and 40% on S. aureus and E. Coli bacteria showed growth inhibition activity of these two bacteria, the largest diameter of the inhibition zone was formed when the extract was given a concentration of 40% with a diameter of the area. Resistance of 8,07 mm and 11 mm, respectively. Meanwhile, the test results of inhibition of growth of the fungus C. Albicans by presenting variations in the concentration of jangjingki methanol extract of 5, 10, 15, and 20% could not inhibit the growth fungus C. Albicans.

https://doi.org/10.36490/journal-jps.com.v4i1.58
PDF

References

Ahmed, D., Zara, S., &Baig, H. (2013). In vitro analysis of antioxidant activities of Oxalis corniculata Linn. fractions in various solvents, 10(1), 158-165.

Ajizah, A. (2004). Sensitivitas Salmonella typhimurium Terhadap Ekstrak Daun Psidium guajava L.. BIOSCIENTIAE, 1(1), 31-38.

Anief, M. (2010). Ilmu Meracik Obat. Penerbit Universitas Gadjah Mada Press, Yogyakarta.

Astuti, E., Sunarminingsih, R., Jenie, U. A., Mubarika, S., & Sismindari. (2014). Pengaruh Lokasi Tumbuh, Umur Tanaman dan Variasi Jenis Destilasi Terhadap Komposisi Senyawa Minyak AtsiriRimpangCurcuma mangga Produksi Beberapa Sentra di Yogyakarta. J Manusia dan Lingkungan, 21(3), 323-330.

Brooks, G.F., Janet, S.B., &Stephen, A.M. (2007). Jawetz, Melnick and Adelbergs, Mikrobiologi Kedokteran edisi23. Terjemahan oleh Mudihardi, E., Kuntaman, Wasito, E.B., Mertaniasih, N.M., Harsono, S., dan Alimsardjono, L. Penerbit Buku Kedokteran EGC, Jakarta.

Candrasari, A., Romas, M. A., Hasbi, M.,&Astuti, O. R. (2012). Uji Daya Antimikroba Ekstrak Etanol Daun Sirih Merah (Piper Crocatum Ruiz & Pav.) Terhadap Pertumbuhan Staphylococcus AureusATCC 6538, Eschericia ColiATCC 11229 dan Candida AlbicansATCC10231 secara In Vitro. Biomedika, 4(1), 9-16.

Clinical and Laboratory Standards Institute. (2018). Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Fourth Informational Supplement 28th ed. CLSI document M100-S24, USA.

Denovix Inc. (2017). OD600 Measurement. Denovix, Us.

Departemen Kesehatan Republik Indonesia. (2000). Parameter Standar Umum Ekstrak Tumbuhan Obat edisi kesatu. Direktorat Jendral Pengawasan Obat dan Makanan, Jakarta.

Dighe, S. B., Kuchekar, B. S., & Wankhede, S. B. (2012). Pharmacological Evaluation of Oxalis corniculata Linn for Anthelmintic Activity. Journal of Pharmacology and Pharmacodynamics, 4(1), 1-4.

Dzulkarnain, B., Sundari, D.,&Chozin, A.(2004). Tanaman Obat Bersifat Antibakteri di Indonesia. Cermin Dunia Kedokteran, 110, 35-43.

Ernawati & Sari, K. (2015). Kandungan Senyawa Kimia dan Aktivitas Antibakteri Ekstrak Kulit Buah Alpukat (Persea americana P.Mill) Terhadap Bakteri Vibrio alginolyticus. Jurnal Kajian Veteriner, 3(2), 203-211.

Gayo, R. P.(2018). Uji Efek Antelmintik Ekstrak Metanol Jangjingki (Oxalis corniculataL.) Terhadap Cacing Ascaridia gallisecara In Vitro (Tugas Akhir). Universitas Syiah Kuala, Banda Aceh.

Handali, S., Hosseini, H., Ameri, A., & Moghimipour, E. (2011). Formulation and evaluation of an antibacterial cream from Oxalis corniculata aqueous extract. Jundishapur Journal of Microbiology, 4(4), 255-260.

Herwin & Nuryanti, S. (2012). SkriningAktivitas Antimikroba Ekstrak Herba Belimbing Tanah (Oxalis Corniculata L.) secara KLT-Bioautografi dan Difusi Agar. As-Syifaa, 4(1), 74-81.

Husni, E., Suharti, N., & Atma, A. P. T. (2018). Karakterisasi Simplisia dan Ekstrak Daun Pacar Kuku (Lawsonia inermis Linn) serta Penentuan Kadar Fenolat Total dan Uji Aktivitas Antioksidan. Jurnal Sains Farmasi dan Klinis, 5(1), 12-16.

Juliantina, F. R., Citra, D. A. M., Nirwani, B., Nurmasitoh, T., & Bowo, E. T. (2008). Manfaat Sirih Merah (Piper crocatum) sebagai Agen Anti Bakterial Terhadap Bakteri Gram Positif dan Gram Negatif. JKKI - Jurnal Kedokteran dan Kesehatan Indonesia, 1(1), 12-20.

Kusumawati, E., Supriningrum, R., & Rozadi, R. (2015). Uji Aktivitas Antibakteri Ekstrak Etanol Daun Kecombrang Etlingera elatior (Jack) R.M.Sm Terhadap Salmonella typhi. Jurnal Ilmiah Manuntung, 1(1), 1-7.

Lingga, A. R., Pato, U., & Rossi, E. (2016). UjiAntibakteri Ekstrak Batang Kecombrang (Nicolaia speciosa Horan) Terhadap Staphylococcus aureusdanEscherichia coli. JOM Faperta, 3(1), 1-15.

Litaay, M., Sari, K., Gobel, R. B., & Haedar, N. (2017). Potensi Abalon Tropis Haliotis asinina L. Sebagai Sumber Inokulum Jamur Simbion Penghasil Antimikroba. SPERMONDE, 3(1), 42-46.

Menteri Kesehatan Republik Indonesia. (2009). FarmakopeHerbal Indonesia edisi pertama. Kementerian Kesehatan RI, Jakarta.

Mohan, S. M., & Pandey, B. (2016). Antimicrobial Activity of Oxalis corniculata Linn.International Journal of Science and Research, 5(7), 575-578.

Mutiawati, V. K. (2016). Pemeriksaan Mikrobiologi pada Candida albicans.Jurnal Kedokteran Syiah Kuala, 16(1), 53-63.

Ningsih, D. R., Zusfahair., & Kartika, D. (2016). Identifikasi Senyawa Metabolit Sekunder serta Uji Aktivitas Ekstrak Daun Sirsak Sebagai Antibakteri. Molekul, 11(1), 101-111.

Nur, R. M., Mu’nisa, A., & Hala, Y. (2019). Skrining Fitokimia Ekstrak Metanol Karang Lunak (Lobophytum sp.). Jurnal Bionature, 20(1), 57-63.

Nuryanti, S., Mustapa, K., & Sudarmo, I. G. (2016). Uji Daya Hambat Ekstrak Buah Kelor (Moringa oleifera Lamk) Terhadap Pertumbuhan Jamur Candida albicans. Jurnal Akademika Kimia, 5(4), 178-184.

Pratiwi, S. T. (2008). Mikrobiologi Farmasi. Erlangga, Jakarta

Reo, A. R., Berhimpon, S., & Montolalu, R. (2017). Metabolit Sekunder Gorgonia (Paramuricea clavata). Jurnal Ilmiah Platax, 5(1), 42-48.

Salman, S. (2018). Use Of Grid Computing Infrastructures For In-Silico Drug Discovery And Drug Design: A Review. Jurnal Stikna, 2(2).

Segismundo, A. B., Florendo, P. E., &Pablico, A. R. P. (2008). In vitro Antifungal Activity and Phytochemical Screening of Gouania javanica Miq. Leaves. UNP Research Journal, 17, 1-10.

Siddiqui, M. A., Singh, R. K.& Kumar, A.(2017). Phytochemical screening and antibacterial activity of Oxalis corniculata against human pathogens. International Journal of Current Research, 9(12), 62114-62118.

Suryani, N., Nurjanah, D., & Indriatmoko, D. D. (2019). Aktivitas Antibakteri Ekstrak Batang Kecombrang (Etlingera elatior (Jack) R.M.Sm.) Terhadap Bakteri Plak Gigi Streptococcus mutans. Jurnal Kartika Kimia, 2(1), 23-29.

Tansil, A. Y. M., Nangoy, E., Posangi, J., & Bara, R. A. (2016). Uji Daya Hambat Ekstrak Etanol Daun Srikaya (Annona squamosa) Terhadap Pertumbuhan Bakteri Escherichia coli dan Staphylococcus aureus. Jurnal e-Biomedik (eBm), 4(2).

Tibuhwa, D. D. (2016). Oxalis corniculata L. In Tanzania: traditional use, cytotoxicity, and antimicrobial activities. Journal of Applied Biosciences, 105, 10055-10063.

Tyasrini, E., Winata, T., & Susantina. (2006). Hubungan antara Sifat dan Metabolit Candida spp. dengan Patogenesis Kandidiasis. JKM, 6(1), 52-67.

Wiyanto, D. B. (2010). Uji Aktivitas Antibakteri Ekstrak Rumput Laut Kappaphycus alvareziidanEucheuma denticullatumTerhadap BakteriAeromonas hydrophiladanVibrio harveyii. Jurnal Kelautan, 3(1), 1-17.

World Health Organization. (2003). Manual for the Laboratory Identification and Antimicrobial Susceptibility Testing of Bacterial Pathogens of Public Health Importance in the Developing World. Switzerland.

World Health Organization. (2009). WHO Laboratory Manual for Diagnosis of Fungal Opportunistic Infection in HIV/AIDS Patients, Regional Office for South-East Asia.

Yusriana, C. S., Budi, C. S.,&Dewi, T. (2014). Uji Daya Hambat Infusa Daun Nangka (Artocarpus heterophyllus) Terhadap Pertumbuhan Bakteri Staphylococcus aureus. Jurnal Permata Indonesia, 5(2), 1-7.

Creative Commons License

This work is licensed under a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International License.

Downloads

Download data is not yet available.